Comparison of two devices to simulate vision with intraocular lenses

Siegfried Wahl,1,2 Chengyang Song,1 Arne Ohlendorf1,2 1Institute for Ophthalmic Research, Eberhard Karls University Tuebingen, Tuebingen, Baden-Wuerttemberg, Germany; 2Technology and Innovation, Carl Zeiss Vision International GmbH, Aalen, Baden-Wuerttemberg, Germany Introduction: The simulation o...

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Autores principales:	Wahl S, Song C, Ohlendorf A
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	contrast sensitivity cataract vision psychophysics Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/2192f17135904d9a89b6e05284bff093
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spelling	oai:doaj.org-article:2192f17135904d9a89b6e05284bff0932021-12-02T02:47:49ZComparison of two devices to simulate vision with intraocular lenses1177-5483https://doaj.org/article/2192f17135904d9a89b6e05284bff0932019-01-01T00:00:00Zhttps://www.dovepress.com/comparison-of-two-devices-to-simulate-vision-with-intraocular-lenses-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Siegfried Wahl,1,2 Chengyang Song,1 Arne Ohlendorf1,2 1Institute for Ophthalmic Research, Eberhard Karls University Tuebingen, Tuebingen, Baden-Wuerttemberg, Germany; 2Technology and Innovation, Carl Zeiss Vision International GmbH, Aalen, Baden-Wuerttemberg, Germany Introduction: The simulation of vision with intraocular lenses (IOLs) prior to the clinical validation is of great interest for manufacturers as well as clinicians. We have tested the influence of different IOLs on the perception of contrast using different devices.Materials and methods: A Rassow telescope and the VirtIOL have been used to assess the contrast sensitivity function (CSF) through monfocal IOL (CT Asphina 409 MP, IOL 1), multifocal IOL (AT LISA tri 839 MP, IOL 2) and extended-depth-of-focus-IOL (TECNIS Symfony ZXR00, IOL3) in 21 participants, aged between 22 and 29 years. Contrast sensitivity (CS) was tested at various spatial frequencies (3–30 cycles per degree), using the Tuebingen contrast sensitivity test.Results: All tested IOL reduced the CS when compared to measurements with a trial lens correction of refractive errors. The analysis of the area under the curve of the contrast sensitivity function (AUC-CSF) revealed a significant reduction compared to the trial lens correction in case the Rassow telescope was used (IOL 1: P=0.008; IOL2: P<0.001; IOL3: P<0.001) and the same was true for the VirtIOL device for IOL2 and IOL3 (IOL2: P<0.001; IOL3: P<0.001), but not for IOL1 (P=0.192). Interdevice analysis of the AUC-CSF revealed significant differences for IOL1 and IOL2 (IOL1: P=0.025; IOL2: P<0.001), while no difference was found for IOL3 (P=0.092). Bland–Altman analysis as well as intraclass correlations coefficients indicated only weak interdevice agreement for the tested IOL.Conclusion: The assessment of the interdevice analysis for the Rassow telescope and the VirtIOL device revealed only a minor agreement between the two devices. In order to investigate vision with IOLs prior to a clinical validation, the use of the VirtIOL device is recommended. Keywords: contrast sensitivity, cataract, vision, psychophysicsWahl SSong COhlendorf ADove Medical Pressarticlecontrast sensitivitycataractvisionpsychophysicsOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 13, Pp 123-130 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	contrast sensitivity cataract vision psychophysics Ophthalmology RE1-994
spellingShingle	contrast sensitivity cataract vision psychophysics Ophthalmology RE1-994 Wahl S Song C Ohlendorf A Comparison of two devices to simulate vision with intraocular lenses
description	Siegfried Wahl,1,2 Chengyang Song,1 Arne Ohlendorf1,2 1Institute for Ophthalmic Research, Eberhard Karls University Tuebingen, Tuebingen, Baden-Wuerttemberg, Germany; 2Technology and Innovation, Carl Zeiss Vision International GmbH, Aalen, Baden-Wuerttemberg, Germany Introduction: The simulation of vision with intraocular lenses (IOLs) prior to the clinical validation is of great interest for manufacturers as well as clinicians. We have tested the influence of different IOLs on the perception of contrast using different devices.Materials and methods: A Rassow telescope and the VirtIOL have been used to assess the contrast sensitivity function (CSF) through monfocal IOL (CT Asphina 409 MP, IOL 1), multifocal IOL (AT LISA tri 839 MP, IOL 2) and extended-depth-of-focus-IOL (TECNIS Symfony ZXR00, IOL3) in 21 participants, aged between 22 and 29 years. Contrast sensitivity (CS) was tested at various spatial frequencies (3–30 cycles per degree), using the Tuebingen contrast sensitivity test.Results: All tested IOL reduced the CS when compared to measurements with a trial lens correction of refractive errors. The analysis of the area under the curve of the contrast sensitivity function (AUC-CSF) revealed a significant reduction compared to the trial lens correction in case the Rassow telescope was used (IOL 1: P=0.008; IOL2: P<0.001; IOL3: P<0.001) and the same was true for the VirtIOL device for IOL2 and IOL3 (IOL2: P<0.001; IOL3: P<0.001), but not for IOL1 (P=0.192). Interdevice analysis of the AUC-CSF revealed significant differences for IOL1 and IOL2 (IOL1: P=0.025; IOL2: P<0.001), while no difference was found for IOL3 (P=0.092). Bland–Altman analysis as well as intraclass correlations coefficients indicated only weak interdevice agreement for the tested IOL.Conclusion: The assessment of the interdevice analysis for the Rassow telescope and the VirtIOL device revealed only a minor agreement between the two devices. In order to investigate vision with IOLs prior to a clinical validation, the use of the VirtIOL device is recommended. Keywords: contrast sensitivity, cataract, vision, psychophysics
format	article
author	Wahl S Song C Ohlendorf A
author_facet	Wahl S Song C Ohlendorf A
author_sort	Wahl S
title	Comparison of two devices to simulate vision with intraocular lenses
title_short	Comparison of two devices to simulate vision with intraocular lenses
title_full	Comparison of two devices to simulate vision with intraocular lenses
title_fullStr	Comparison of two devices to simulate vision with intraocular lenses
title_full_unstemmed	Comparison of two devices to simulate vision with intraocular lenses
title_sort	comparison of two devices to simulate vision with intraocular lenses
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/2192f17135904d9a89b6e05284bff093
work_keys_str_mv	AT wahls comparisonoftwodevicestosimulatevisionwithintraocularlenses AT songc comparisonoftwodevicestosimulatevisionwithintraocularlenses AT ohlendorfa comparisonoftwodevicestosimulatevisionwithintraocularlenses
_version_	1718402149169233920

Comparison of two devices to simulate vision with intraocular lenses

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