Myocardial and Microvascular Injury Due to Coronavirus Disease 2019

Over the past few months, health systems worldwide have been put to the test with the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Even though the leading clinical manifestations of the SARS-CoV-2 infection involve the respirato...

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Autores principales: Rocco A Montone, Giulia Iannaccone, Maria Chiara Meucci, Filippo Gurgoglione, Giampaolo Niccoli
Formato: article
Lenguaje:EN
Publicado: Radcliffe Medical Media 2020
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Acceso en línea:https://doaj.org/article/21ab3b263d704cb68eb18440257533f9
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spelling oai:doaj.org-article:21ab3b263d704cb68eb18440257533f92021-12-04T16:03:13ZMyocardial and Microvascular Injury Due to Coronavirus Disease 201910.15420/ecr.2020.221758-37641758-3756https://doaj.org/article/21ab3b263d704cb68eb18440257533f92020-06-01T00:00:00Zhttps://www.ecrjournal.com/articleindex/ecr.2020.22https://doaj.org/toc/1758-3756https://doaj.org/toc/1758-3764Over the past few months, health systems worldwide have been put to the test with the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Even though the leading clinical manifestations of the SARS-CoV-2 infection involve the respiratory tract, there is a non-negligible risk of systemic involvement leading to the onset of multi-organ failure with fatal consequences. Since the onset of COVID-19, patients with underlying cardiovascular disease have been at increased risk of poor clinical outcomes with higher death rates. Moreover, the occurrence of new-onset cardiac complications is not uncommon among patients hospitalised for COVID-19. Of importance, a significant portion of COVID-19 patients present with myocardial injury. Herein, the authors discuss the mechanisms leading to myocardial and microvascular injury in SARS-CoV-2 infection and their clinical implications.Rocco A MontoneGiulia IannacconeMaria Chiara MeucciFilippo GurgoglioneGiampaolo NiccoliRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENEuropean Cardiology Review , Vol 15, Iss , Pp - (2020)
institution DOAJ
collection DOAJ
language EN
topic Diseases of the circulatory (Cardiovascular) system
RC666-701
spellingShingle Diseases of the circulatory (Cardiovascular) system
RC666-701
Rocco A Montone
Giulia Iannaccone
Maria Chiara Meucci
Filippo Gurgoglione
Giampaolo Niccoli
Myocardial and Microvascular Injury Due to Coronavirus Disease 2019
description Over the past few months, health systems worldwide have been put to the test with the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Even though the leading clinical manifestations of the SARS-CoV-2 infection involve the respiratory tract, there is a non-negligible risk of systemic involvement leading to the onset of multi-organ failure with fatal consequences. Since the onset of COVID-19, patients with underlying cardiovascular disease have been at increased risk of poor clinical outcomes with higher death rates. Moreover, the occurrence of new-onset cardiac complications is not uncommon among patients hospitalised for COVID-19. Of importance, a significant portion of COVID-19 patients present with myocardial injury. Herein, the authors discuss the mechanisms leading to myocardial and microvascular injury in SARS-CoV-2 infection and their clinical implications.
format article
author Rocco A Montone
Giulia Iannaccone
Maria Chiara Meucci
Filippo Gurgoglione
Giampaolo Niccoli
author_facet Rocco A Montone
Giulia Iannaccone
Maria Chiara Meucci
Filippo Gurgoglione
Giampaolo Niccoli
author_sort Rocco A Montone
title Myocardial and Microvascular Injury Due to Coronavirus Disease 2019
title_short Myocardial and Microvascular Injury Due to Coronavirus Disease 2019
title_full Myocardial and Microvascular Injury Due to Coronavirus Disease 2019
title_fullStr Myocardial and Microvascular Injury Due to Coronavirus Disease 2019
title_full_unstemmed Myocardial and Microvascular Injury Due to Coronavirus Disease 2019
title_sort myocardial and microvascular injury due to coronavirus disease 2019
publisher Radcliffe Medical Media
publishDate 2020
url https://doaj.org/article/21ab3b263d704cb68eb18440257533f9
work_keys_str_mv AT roccoamontone myocardialandmicrovascularinjuryduetocoronavirusdisease2019
AT giuliaiannaccone myocardialandmicrovascularinjuryduetocoronavirusdisease2019
AT mariachiarameucci myocardialandmicrovascularinjuryduetocoronavirusdisease2019
AT filippogurgoglione myocardialandmicrovascularinjuryduetocoronavirusdisease2019
AT giampaoloniccoli myocardialandmicrovascularinjuryduetocoronavirusdisease2019
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