Primary Yolk Sac Tumor in the Cerebellar Hemisphere: A Case Report and Literature Review of the Rare Tumor

Yolk sac tumor (YST) is one of rare malignant germ cell tumors (GCTs). Primary intracranial YST, also endodermal sinus tumor (EST), is a quite rare type of brain tumor. Here, we report a case of YST, review the relevant literature, and propose a treatment strategy for this rare tumor. A 6-year-old b...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Na Wu, Qiang Chen, Meng Chen, Jinbo Ning, Shulei Peng, Taotao Zhang, Wen Zhong, Song Duan, Chongjie Cheng, Yimin Xie
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	yolk sac tumor cerebellar hemisphere endodermal sinus tumor microsurgery subtotal resection Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/21ad369df25f49f79d19d255034e8e48
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:21ad369df25f49f79d19d255034e8e48
record_format	dspace
spelling	oai:doaj.org-article:21ad369df25f49f79d19d255034e8e482021-11-05T05:32:09ZPrimary Yolk Sac Tumor in the Cerebellar Hemisphere: A Case Report and Literature Review of the Rare Tumor2234-943X10.3389/fonc.2021.739733https://doaj.org/article/21ad369df25f49f79d19d255034e8e482021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fonc.2021.739733/fullhttps://doaj.org/toc/2234-943XYolk sac tumor (YST) is one of rare malignant germ cell tumors (GCTs). Primary intracranial YST, also endodermal sinus tumor (EST), is a quite rare type of brain tumor. Here, we report a case of YST, review the relevant literature, and propose a treatment strategy for this rare tumor. A 6-year-old boy initially manifested symptoms of dizziness and vomiting. Computed tomography (CT) and magnetic resonance imaging (MRI) showed a large irregular oval tumor in the cerebellar hemisphere. We subtotally removed the tumor by microsurgery through the left suboccipital approach. Immunohistochemical staining showed that alpha fetoprotein (AFP) was positive and the Ki-67 proliferation index was high (60%), suggesting a germ cell tumor. After 3 months of follow-up, neither recurrence of tumor nor complications were found in the patient. The diagnosis of YST should be confirmed on the basis of clinical manifestations, neuroimaging and pathological findings. Gross total resection (GTR) is an ideal treatment for YST. However, due to the location of the tumor, GTR is usually difficult, and the rate of postoperative complications is high. This reported case shows that subtotal resection can be a good treatment strategy for YST.Na WuQiang ChenMeng ChenJinbo NingShulei PengTaotao ZhangWen ZhongSong DuanChongjie ChengYimin XieFrontiers Media S.A.articleyolk sac tumorcerebellar hemisphereendodermal sinus tumormicrosurgerysubtotal resectionNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENFrontiers in Oncology, Vol 11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	yolk sac tumor cerebellar hemisphere endodermal sinus tumor microsurgery subtotal resection Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	yolk sac tumor cerebellar hemisphere endodermal sinus tumor microsurgery subtotal resection Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Na Wu Qiang Chen Meng Chen Jinbo Ning Shulei Peng Taotao Zhang Wen Zhong Song Duan Chongjie Cheng Yimin Xie Primary Yolk Sac Tumor in the Cerebellar Hemisphere: A Case Report and Literature Review of the Rare Tumor
description	Yolk sac tumor (YST) is one of rare malignant germ cell tumors (GCTs). Primary intracranial YST, also endodermal sinus tumor (EST), is a quite rare type of brain tumor. Here, we report a case of YST, review the relevant literature, and propose a treatment strategy for this rare tumor. A 6-year-old boy initially manifested symptoms of dizziness and vomiting. Computed tomography (CT) and magnetic resonance imaging (MRI) showed a large irregular oval tumor in the cerebellar hemisphere. We subtotally removed the tumor by microsurgery through the left suboccipital approach. Immunohistochemical staining showed that alpha fetoprotein (AFP) was positive and the Ki-67 proliferation index was high (60%), suggesting a germ cell tumor. After 3 months of follow-up, neither recurrence of tumor nor complications were found in the patient. The diagnosis of YST should be confirmed on the basis of clinical manifestations, neuroimaging and pathological findings. Gross total resection (GTR) is an ideal treatment for YST. However, due to the location of the tumor, GTR is usually difficult, and the rate of postoperative complications is high. This reported case shows that subtotal resection can be a good treatment strategy for YST.
format	article
author	Na Wu Qiang Chen Meng Chen Jinbo Ning Shulei Peng Taotao Zhang Wen Zhong Song Duan Chongjie Cheng Yimin Xie
author_facet	Na Wu Qiang Chen Meng Chen Jinbo Ning Shulei Peng Taotao Zhang Wen Zhong Song Duan Chongjie Cheng Yimin Xie
author_sort	Na Wu
title	Primary Yolk Sac Tumor in the Cerebellar Hemisphere: A Case Report and Literature Review of the Rare Tumor
title_short	Primary Yolk Sac Tumor in the Cerebellar Hemisphere: A Case Report and Literature Review of the Rare Tumor
title_full	Primary Yolk Sac Tumor in the Cerebellar Hemisphere: A Case Report and Literature Review of the Rare Tumor
title_fullStr	Primary Yolk Sac Tumor in the Cerebellar Hemisphere: A Case Report and Literature Review of the Rare Tumor
title_full_unstemmed	Primary Yolk Sac Tumor in the Cerebellar Hemisphere: A Case Report and Literature Review of the Rare Tumor
title_sort	primary yolk sac tumor in the cerebellar hemisphere: a case report and literature review of the rare tumor
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/21ad369df25f49f79d19d255034e8e48
work_keys_str_mv	AT nawu primaryyolksactumorinthecerebellarhemisphereacasereportandliteraturereviewoftheraretumor AT qiangchen primaryyolksactumorinthecerebellarhemisphereacasereportandliteraturereviewoftheraretumor AT mengchen primaryyolksactumorinthecerebellarhemisphereacasereportandliteraturereviewoftheraretumor AT jinboning primaryyolksactumorinthecerebellarhemisphereacasereportandliteraturereviewoftheraretumor AT shuleipeng primaryyolksactumorinthecerebellarhemisphereacasereportandliteraturereviewoftheraretumor AT taotaozhang primaryyolksactumorinthecerebellarhemisphereacasereportandliteraturereviewoftheraretumor AT wenzhong primaryyolksactumorinthecerebellarhemisphereacasereportandliteraturereviewoftheraretumor AT songduan primaryyolksactumorinthecerebellarhemisphereacasereportandliteraturereviewoftheraretumor AT chongjiecheng primaryyolksactumorinthecerebellarhemisphereacasereportandliteraturereviewoftheraretumor AT yiminxie primaryyolksactumorinthecerebellarhemisphereacasereportandliteraturereviewoftheraretumor
_version_	1718444454902235136

Primary Yolk Sac Tumor in the Cerebellar Hemisphere: A Case Report and Literature Review of the Rare Tumor

Ejemplares similares