Restoration of HBV-specific CD8+ T-cell responses by sequential low-dose IL-2 treatment in non-responder patients after IFN-α therapy

Restoration of HBV-specific CD8+ T-cell responses by sequential low-dose IL-2 treatment in non-responder patients after IFN-α therapy

Abstract Patients with chronic hepatitis B (CHB) undergoing interferon (IFN)-α-based therapies often exhibit a poor HBeAg serological response. Thus, there is an unmet need for new therapies aimed at CHB. This study comprised two clinical trials, including 130 CHB patients, who were treatment-naïve;...

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Autores principales: Dongyao Wang, Binqing Fu, Xiaokun Shen, Chuang Guo, Yanyan Liu, Junfei Zhang, Rui Sun, Ying Ye, Jiabin Li, Zhigang Tian, Haiming Wei
Formato: article
Lenguaje:EN
Publicado: Nature Publishing Group 2021
Materias:
Medicine
R
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/21b417eb6d294715b19d0a664f3c43a8
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