TNIK signaling imprints CD8+ T cell memory formation early after priming

TNIK signaling imprints CD8+ T cell memory formation early after priming

Coordinate expression of multiple factors play critical roles in the regulation between effector and memory CD8+ T cell differentiation. Here the authors show upon acute viral infection TNIK is critically required as a regulator of effector and memory T cell differentiation.

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Detalles Bibliográficos
Autores principales: Carla A. Jaeger-Ruckstuhl, Magdalena Hinterbrandner, Sabine Höpner, Colin E. Correnti, Ursina Lüthi, Olivier Friedli, Stefan Freigang, Mohamad F. Al Sayed, Elias D. Bührer, Michael A. Amrein, Christian M. Schürch, Ramin Radpour, Carsten Riether, Adrian F. Ochsenbein
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/21c39ff478914e4584620912b78764da
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Descripción
Sumario:Coordinate expression of multiple factors play critical roles in the regulation between effector and memory CD8+ T cell differentiation. Here the authors show upon acute viral infection TNIK is critically required as a regulator of effector and memory T cell differentiation.

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