TNIK signaling imprints CD8+ T cell memory formation early after priming

Coordinate expression of multiple factors play critical roles in the regulation between effector and memory CD8+ T cell differentiation. Here the authors show upon acute viral infection TNIK is critically required as a regulator of effector and memory T cell differentiation.

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Autores principales: Carla A. Jaeger-Ruckstuhl, Magdalena Hinterbrandner, Sabine Höpner, Colin E. Correnti, Ursina Lüthi, Olivier Friedli, Stefan Freigang, Mohamad F. Al Sayed, Elias D. Bührer, Michael A. Amrein, Christian M. Schürch, Ramin Radpour, Carsten Riether, Adrian F. Ochsenbein
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/21c39ff478914e4584620912b78764da
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spelling oai:doaj.org-article:21c39ff478914e4584620912b78764da2021-12-02T14:25:14ZTNIK signaling imprints CD8+ T cell memory formation early after priming10.1038/s41467-020-15413-72041-1723https://doaj.org/article/21c39ff478914e4584620912b78764da2020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15413-7https://doaj.org/toc/2041-1723Coordinate expression of multiple factors play critical roles in the regulation between effector and memory CD8+ T cell differentiation. Here the authors show upon acute viral infection TNIK is critically required as a regulator of effector and memory T cell differentiation.Carla A. Jaeger-RuckstuhlMagdalena HinterbrandnerSabine HöpnerColin E. CorrentiUrsina LüthiOlivier FriedliStefan FreigangMohamad F. Al SayedElias D. BührerMichael A. AmreinChristian M. SchürchRamin RadpourCarsten RietherAdrian F. OchsenbeinNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Carla A. Jaeger-Ruckstuhl
Magdalena Hinterbrandner
Sabine Höpner
Colin E. Correnti
Ursina Lüthi
Olivier Friedli
Stefan Freigang
Mohamad F. Al Sayed
Elias D. Bührer
Michael A. Amrein
Christian M. Schürch
Ramin Radpour
Carsten Riether
Adrian F. Ochsenbein
TNIK signaling imprints CD8+ T cell memory formation early after priming
description Coordinate expression of multiple factors play critical roles in the regulation between effector and memory CD8+ T cell differentiation. Here the authors show upon acute viral infection TNIK is critically required as a regulator of effector and memory T cell differentiation.
format article
author Carla A. Jaeger-Ruckstuhl
Magdalena Hinterbrandner
Sabine Höpner
Colin E. Correnti
Ursina Lüthi
Olivier Friedli
Stefan Freigang
Mohamad F. Al Sayed
Elias D. Bührer
Michael A. Amrein
Christian M. Schürch
Ramin Radpour
Carsten Riether
Adrian F. Ochsenbein
author_facet Carla A. Jaeger-Ruckstuhl
Magdalena Hinterbrandner
Sabine Höpner
Colin E. Correnti
Ursina Lüthi
Olivier Friedli
Stefan Freigang
Mohamad F. Al Sayed
Elias D. Bührer
Michael A. Amrein
Christian M. Schürch
Ramin Radpour
Carsten Riether
Adrian F. Ochsenbein
author_sort Carla A. Jaeger-Ruckstuhl
title TNIK signaling imprints CD8+ T cell memory formation early after priming
title_short TNIK signaling imprints CD8+ T cell memory formation early after priming
title_full TNIK signaling imprints CD8+ T cell memory formation early after priming
title_fullStr TNIK signaling imprints CD8+ T cell memory formation early after priming
title_full_unstemmed TNIK signaling imprints CD8+ T cell memory formation early after priming
title_sort tnik signaling imprints cd8+ t cell memory formation early after priming
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/21c39ff478914e4584620912b78764da
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