A Facile and Flexible Method for On-Demand Directional Speed Tunability in the Miniaturised Lab-on-a-Disc

Abstract The Miniaturised Lab-on-a-Disc (miniLOAD) platform, which utilises surface acoustic waves (SAWs) to drive the rotation of thin millimeter-scale discs on which microchannels can be fabricated and hence microfluidic operations can be performed, offers the possibility of miniaturising its larg...

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Autores principales:	Ming K. Tan, Ariba Siddiqi, Leslie Y. Yeo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/21c3a824556f4425a8f8ce2dc186f164
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spelling	oai:doaj.org-article:21c3a824556f4425a8f8ce2dc186f1642021-12-02T11:40:34ZA Facile and Flexible Method for On-Demand Directional Speed Tunability in the Miniaturised Lab-on-a-Disc10.1038/s41598-017-07025-x2045-2322https://doaj.org/article/21c3a824556f4425a8f8ce2dc186f1642017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-07025-xhttps://doaj.org/toc/2045-2322Abstract The Miniaturised Lab-on-a-Disc (miniLOAD) platform, which utilises surface acoustic waves (SAWs) to drive the rotation of thin millimeter-scale discs on which microchannels can be fabricated and hence microfluidic operations can be performed, offers the possibility of miniaturising its larger counterpart, the Lab-on-a-CD, for true portability in point-of-care applications. A significant limitation of the original miniLOAD concept, however, is that it does not allow for flexible control over the disc rotation direction and speed without manual adjustment of the disc’s position, or the use of multiple devices to alter the SAW frequency. In this work, we demonstrate the possibility of achieving such control with the use of tapered interdigitated transducers to confine a SAW beam such that the localised acoustic streaming it generates imparts a force, through hydrodynamic shear, at a specific location on the disc. Varying the torque that arises as a consequence by altering the input frequency to the transducers then allows the rotational velocity and direction of the disc to be controlled with ease. We derive a simple predictive model to illustrate the principle by which this occurs, which we find agrees well with the experimental measurements.Ming K. TanAriba SiddiqiLeslie Y. YeoNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ming K. Tan Ariba Siddiqi Leslie Y. Yeo A Facile and Flexible Method for On-Demand Directional Speed Tunability in the Miniaturised Lab-on-a-Disc
description	Abstract The Miniaturised Lab-on-a-Disc (miniLOAD) platform, which utilises surface acoustic waves (SAWs) to drive the rotation of thin millimeter-scale discs on which microchannels can be fabricated and hence microfluidic operations can be performed, offers the possibility of miniaturising its larger counterpart, the Lab-on-a-CD, for true portability in point-of-care applications. A significant limitation of the original miniLOAD concept, however, is that it does not allow for flexible control over the disc rotation direction and speed without manual adjustment of the disc’s position, or the use of multiple devices to alter the SAW frequency. In this work, we demonstrate the possibility of achieving such control with the use of tapered interdigitated transducers to confine a SAW beam such that the localised acoustic streaming it generates imparts a force, through hydrodynamic shear, at a specific location on the disc. Varying the torque that arises as a consequence by altering the input frequency to the transducers then allows the rotational velocity and direction of the disc to be controlled with ease. We derive a simple predictive model to illustrate the principle by which this occurs, which we find agrees well with the experimental measurements.
format	article
author	Ming K. Tan Ariba Siddiqi Leslie Y. Yeo
author_facet	Ming K. Tan Ariba Siddiqi Leslie Y. Yeo
author_sort	Ming K. Tan
title	A Facile and Flexible Method for On-Demand Directional Speed Tunability in the Miniaturised Lab-on-a-Disc
title_short	A Facile and Flexible Method for On-Demand Directional Speed Tunability in the Miniaturised Lab-on-a-Disc
title_full	A Facile and Flexible Method for On-Demand Directional Speed Tunability in the Miniaturised Lab-on-a-Disc
title_fullStr	A Facile and Flexible Method for On-Demand Directional Speed Tunability in the Miniaturised Lab-on-a-Disc
title_full_unstemmed	A Facile and Flexible Method for On-Demand Directional Speed Tunability in the Miniaturised Lab-on-a-Disc
title_sort	facile and flexible method for on-demand directional speed tunability in the miniaturised lab-on-a-disc
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/21c3a824556f4425a8f8ce2dc186f164
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A Facile and Flexible Method for On-Demand Directional Speed Tunability in the Miniaturised Lab-on-a-Disc

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