Neurovascular coupling and oxygenation are decreased in hippocampus compared to neocortex because of microvascular differences

The hippocampus is particularly sensitive to hypoxia but it has been difficult to study blood flow in this region. Here the authors compare the neurovascular function of the hippocampus and cortex and in awake mice, and find differences associated with microvascular structure.

Guardado en:

Detalles Bibliográficos
Autores principales:	K. Shaw, L. Bell, K. Boyd, D. M. Grijseels, D. Clarke, O. Bonnar, H. S. Crombag, C. N. Hall
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/21d36d371cfd4d39a816b085ad27ce2b
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:21d36d371cfd4d39a816b085ad27ce2b
record_format	dspace
spelling	oai:doaj.org-article:21d36d371cfd4d39a816b085ad27ce2b2021-12-02T15:49:27ZNeurovascular coupling and oxygenation are decreased in hippocampus compared to neocortex because of microvascular differences10.1038/s41467-021-23508-y2041-1723https://doaj.org/article/21d36d371cfd4d39a816b085ad27ce2b2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23508-yhttps://doaj.org/toc/2041-1723The hippocampus is particularly sensitive to hypoxia but it has been difficult to study blood flow in this region. Here the authors compare the neurovascular function of the hippocampus and cortex and in awake mice, and find differences associated with microvascular structure.K. ShawL. BellK. BoydD. M. GrijseelsD. ClarkeO. BonnarH. S. CrombagC. N. HallNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q K. Shaw L. Bell K. Boyd D. M. Grijseels D. Clarke O. Bonnar H. S. Crombag C. N. Hall Neurovascular coupling and oxygenation are decreased in hippocampus compared to neocortex because of microvascular differences
description	The hippocampus is particularly sensitive to hypoxia but it has been difficult to study blood flow in this region. Here the authors compare the neurovascular function of the hippocampus and cortex and in awake mice, and find differences associated with microvascular structure.
format	article
author	K. Shaw L. Bell K. Boyd D. M. Grijseels D. Clarke O. Bonnar H. S. Crombag C. N. Hall
author_facet	K. Shaw L. Bell K. Boyd D. M. Grijseels D. Clarke O. Bonnar H. S. Crombag C. N. Hall
author_sort	K. Shaw
title	Neurovascular coupling and oxygenation are decreased in hippocampus compared to neocortex because of microvascular differences
title_short	Neurovascular coupling and oxygenation are decreased in hippocampus compared to neocortex because of microvascular differences
title_full	Neurovascular coupling and oxygenation are decreased in hippocampus compared to neocortex because of microvascular differences
title_fullStr	Neurovascular coupling and oxygenation are decreased in hippocampus compared to neocortex because of microvascular differences
title_full_unstemmed	Neurovascular coupling and oxygenation are decreased in hippocampus compared to neocortex because of microvascular differences
title_sort	neurovascular coupling and oxygenation are decreased in hippocampus compared to neocortex because of microvascular differences
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/21d36d371cfd4d39a816b085ad27ce2b
work_keys_str_mv	AT kshaw neurovascularcouplingandoxygenationaredecreasedinhippocampuscomparedtoneocortexbecauseofmicrovasculardifferences AT lbell neurovascularcouplingandoxygenationaredecreasedinhippocampuscomparedtoneocortexbecauseofmicrovasculardifferences AT kboyd neurovascularcouplingandoxygenationaredecreasedinhippocampuscomparedtoneocortexbecauseofmicrovasculardifferences AT dmgrijseels neurovascularcouplingandoxygenationaredecreasedinhippocampuscomparedtoneocortexbecauseofmicrovasculardifferences AT dclarke neurovascularcouplingandoxygenationaredecreasedinhippocampuscomparedtoneocortexbecauseofmicrovasculardifferences AT obonnar neurovascularcouplingandoxygenationaredecreasedinhippocampuscomparedtoneocortexbecauseofmicrovasculardifferences AT hscrombag neurovascularcouplingandoxygenationaredecreasedinhippocampuscomparedtoneocortexbecauseofmicrovasculardifferences AT cnhall neurovascularcouplingandoxygenationaredecreasedinhippocampuscomparedtoneocortexbecauseofmicrovasculardifferences
_version_	1718385678028374016

Neurovascular coupling and oxygenation are decreased in hippocampus compared to neocortex because of microvascular differences

Ejemplares similares