FEATURES OF CELLULAR AND HUMORAL IMMUNITY IN PATIENTS WITH EXTENSIVE PURULENT PERITONITIS

We investigated immunological parameters in patients with extensive purulent peritonitis (EPP). It is established that the EPP revealed an imbalance in the immune system which is characterized by a deficiency of cellular part and increased activity of the humoral. Status of cellular immunity is dete...

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Autores principales: A. A. Savchenko, D. E. Zditovetskiy, A. G. Borisov, N. A. Luzan
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Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2012
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Acceso en línea:https://doaj.org/article/21ed04171d0b4913b2f480db3486789a
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spelling oai:doaj.org-article:21ed04171d0b4913b2f480db3486789a2021-11-23T06:14:19ZFEATURES OF CELLULAR AND HUMORAL IMMUNITY IN PATIENTS WITH EXTENSIVE PURULENT PERITONITIS2541-94202587-9596https://doaj.org/article/21ed04171d0b4913b2f480db3486789a2012-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/909https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596We investigated immunological parameters in patients with extensive purulent peritonitis (EPP). It is established that the EPP revealed an imbalance in the immune system which is characterized by a deficiency of cellular part and increased activity of the humoral. Status of cellular immunity is determined by the decrease in the EPP number of T- (primarily through fractions of cytotoxic T-lymphocytes and expressing of late activation. marker), NK- and NKT-cells. In the peripheral blood of patients with EPP increases the content of Th-cells and B1-lymphocytes. Status humoral immunity in the EPP is characterized by increased Ig A and Ig G levels. With the help of correlation analysis and the separate definition of the entropy of the lymphocytes phenotypic composition and immunoglobulins found an increase in regulatory effect on the humoral immunity.A. A. SavchenkoD. E. ZditovetskiyA. G. BorisovN. A. LuzanScientific Сentre for Family Health and Human Reproduction ProblemsarticleperitonitislymphocytesimmunoglobulinsScienceQRUActa Biomedica Scientifica, Vol 0, Iss 3(2), Pp 159-163 (2012)
institution DOAJ
collection DOAJ
language RU
topic peritonitis
lymphocytes
immunoglobulins
Science
Q
spellingShingle peritonitis
lymphocytes
immunoglobulins
Science
Q
A. A. Savchenko
D. E. Zditovetskiy
A. G. Borisov
N. A. Luzan
FEATURES OF CELLULAR AND HUMORAL IMMUNITY IN PATIENTS WITH EXTENSIVE PURULENT PERITONITIS
description We investigated immunological parameters in patients with extensive purulent peritonitis (EPP). It is established that the EPP revealed an imbalance in the immune system which is characterized by a deficiency of cellular part and increased activity of the humoral. Status of cellular immunity is determined by the decrease in the EPP number of T- (primarily through fractions of cytotoxic T-lymphocytes and expressing of late activation. marker), NK- and NKT-cells. In the peripheral blood of patients with EPP increases the content of Th-cells and B1-lymphocytes. Status humoral immunity in the EPP is characterized by increased Ig A and Ig G levels. With the help of correlation analysis and the separate definition of the entropy of the lymphocytes phenotypic composition and immunoglobulins found an increase in regulatory effect on the humoral immunity.
format article
author A. A. Savchenko
D. E. Zditovetskiy
A. G. Borisov
N. A. Luzan
author_facet A. A. Savchenko
D. E. Zditovetskiy
A. G. Borisov
N. A. Luzan
author_sort A. A. Savchenko
title FEATURES OF CELLULAR AND HUMORAL IMMUNITY IN PATIENTS WITH EXTENSIVE PURULENT PERITONITIS
title_short FEATURES OF CELLULAR AND HUMORAL IMMUNITY IN PATIENTS WITH EXTENSIVE PURULENT PERITONITIS
title_full FEATURES OF CELLULAR AND HUMORAL IMMUNITY IN PATIENTS WITH EXTENSIVE PURULENT PERITONITIS
title_fullStr FEATURES OF CELLULAR AND HUMORAL IMMUNITY IN PATIENTS WITH EXTENSIVE PURULENT PERITONITIS
title_full_unstemmed FEATURES OF CELLULAR AND HUMORAL IMMUNITY IN PATIENTS WITH EXTENSIVE PURULENT PERITONITIS
title_sort features of cellular and humoral immunity in patients with extensive purulent peritonitis
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2012
url https://doaj.org/article/21ed04171d0b4913b2f480db3486789a
work_keys_str_mv AT aasavchenko featuresofcellularandhumoralimmunityinpatientswithextensivepurulentperitonitis
AT dezditovetskiy featuresofcellularandhumoralimmunityinpatientswithextensivepurulentperitonitis
AT agborisov featuresofcellularandhumoralimmunityinpatientswithextensivepurulentperitonitis
AT naluzan featuresofcellularandhumoralimmunityinpatientswithextensivepurulentperitonitis
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