Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers: two case reports

Nicola Ughi, Chiara Crotti, Francesca Ingegnoli Division of Rheumatology, Department of Clinical Sciences and Community Health, Gaetano Pini Institute, The University of Milan, Milan, Italy Abstract: Digital ulcers (DUs) are a severe and frequent clinical feature of patients with systemic sclerosi...

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Autores principales:	Ughi N, Crotti C, Ingegnoli F
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	oxycodone naloxone systemic sclerosis pain digital ulcer scleroderma chronic pain opioids calcinosis UCLA-SCTC GIT 2.0 Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/21fb94400327415a9eaf32c4bda4c238
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spelling	oai:doaj.org-article:21fb94400327415a9eaf32c4bda4c2382021-12-02T00:41:21ZEffectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers: two case reports1178-1998https://doaj.org/article/21fb94400327415a9eaf32c4bda4c2382016-03-01T00:00:00Zhttps://www.dovepress.com/effectiveness-and-safety-of-oxycodonenaloxone-in-the-management-of-chr-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Nicola Ughi, Chiara Crotti, Francesca Ingegnoli Division of Rheumatology, Department of Clinical Sciences and Community Health, Gaetano Pini Institute, The University of Milan, Milan, Italy Abstract: Digital ulcers (DUs) are a severe and frequent clinical feature of patients with systemic sclerosis (SSc). The presence of DUs may cause severe pain and often lead to impairment of patient’s functional activities and health-related quality of life. Moreover, poor patient cooperation during the wound care procedure due to pain may be associated with a negative outcome of DU healing. Therefore, pain management has a key role in patients with SSc. These two case reports describe the effectiveness and safety of oxycodone/naloxone in patients with SSc complicated by painful chronic DUs. Such a therapy has provided pain relief and consequently an increased compliance during redressing wounds. Keywords: oxycodone, naloxone, systemic sclerosis, pain, digital ulcer, scleroderma, analgaesia, wound healing, opioids, calcinosis, UCLA-SCTC GIT 2.0Ughi NCrotti CIngegnoli FDove Medical Pressarticleoxycodonenaloxonesystemic sclerosispaindigital ulcersclerodermachronic painopioidscalcinosisUCLA-SCTC GIT 2.0GeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 11, Pp 307-311 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	oxycodone naloxone systemic sclerosis pain digital ulcer scleroderma chronic pain opioids calcinosis UCLA-SCTC GIT 2.0 Geriatrics RC952-954.6
spellingShingle	oxycodone naloxone systemic sclerosis pain digital ulcer scleroderma chronic pain opioids calcinosis UCLA-SCTC GIT 2.0 Geriatrics RC952-954.6 Ughi N Crotti C Ingegnoli F Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers: two case reports
description	Nicola Ughi, Chiara Crotti, Francesca Ingegnoli Division of Rheumatology, Department of Clinical Sciences and Community Health, Gaetano Pini Institute, The University of Milan, Milan, Italy Abstract: Digital ulcers (DUs) are a severe and frequent clinical feature of patients with systemic sclerosis (SSc). The presence of DUs may cause severe pain and often lead to impairment of patient’s functional activities and health-related quality of life. Moreover, poor patient cooperation during the wound care procedure due to pain may be associated with a negative outcome of DU healing. Therefore, pain management has a key role in patients with SSc. These two case reports describe the effectiveness and safety of oxycodone/naloxone in patients with SSc complicated by painful chronic DUs. Such a therapy has provided pain relief and consequently an increased compliance during redressing wounds. Keywords: oxycodone, naloxone, systemic sclerosis, pain, digital ulcer, scleroderma, analgaesia, wound healing, opioids, calcinosis, UCLA-SCTC GIT 2.0
format	article
author	Ughi N Crotti C Ingegnoli F
author_facet	Ughi N Crotti C Ingegnoli F
author_sort	Ughi N
title	Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers: two case reports
title_short	Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers: two case reports
title_full	Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers: two case reports
title_fullStr	Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers: two case reports
title_full_unstemmed	Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers: two case reports
title_sort	effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers: two case reports
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/21fb94400327415a9eaf32c4bda4c238
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Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers: two case reports

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