Human Cytomegalovirus US28 Ligand Binding Activity Is Required for Latency in CD34<sup>+</sup> Hematopoietic Progenitor Cells and Humanized NSG Mice
ABSTRACT Human cytomegalovirus (HCMV) infection of CD34+ hematopoietic progenitor cells (CD34+ HPCs) provides a critical reservoir of virus in stem cell transplant patients, and viral reactivation remains a significant cause of morbidity and mortality. The HCMV chemokine receptor US28 is implicated...
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Autores principales: | , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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American Society for Microbiology
2019
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Acceso en línea: | https://doaj.org/article/2213cd7c92b0456f946b96b2a577e848 |
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