Loeffler's syndrome in a child: A rare radiological and histopathological diagnosis

Loffler syndrome is an uncommon, self-limited, benign pulmonary eosinophilia that usually lasts less than a month. Abnormal chest radiography occurs in 95% of patients; however, computed tomography findings are not well described. We present clinical features, radiological, and pathological findings...

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Autores principales:	Kiem Hao Tran, A/Prof, PhD, Kim Hoa Nguyen-Thi, MD, Nguyen Cuong Pham, MD, PhD, Cong Thuan Dang, MD, PhD
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2022
Materias:	Loeffler's syndrome Eosinophilia Chest radiograph Computed tomography Medical physics. Medical radiology. Nuclear medicine R895-920
Acceso en línea:	https://doaj.org/article/221827ac28174caba38a49d77b511f80
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spelling	oai:doaj.org-article:221827ac28174caba38a49d77b511f802021-11-30T04:15:21ZLoeffler's syndrome in a child: A rare radiological and histopathological diagnosis1930-043310.1016/j.radcr.2021.10.044https://doaj.org/article/221827ac28174caba38a49d77b511f802022-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1930043321007597https://doaj.org/toc/1930-0433Loffler syndrome is an uncommon, self-limited, benign pulmonary eosinophilia that usually lasts less than a month. Abnormal chest radiography occurs in 95% of patients; however, computed tomography findings are not well described. We present clinical features, radiological, and pathological findings of Loeffler's syndrome with secondary bacterial pneumonia in a child. He presented with dry cough, hemoptysis 2 times, chest pain for 1 week. Blood tests revealed high C-reactive protein levels and eosinophilia. On the initial computed tomography (CT) scan, a lesion was discovered at the upper edge of the right lung hilum. The lesion developed in size, together with right pleural effusion, on the repeated CT scan. A lung biopsy revealed a substantial number of inflammatory cells, including eosinophils and neutrophils. After ruling all other possibilities, Loffler's syndrome was confirmed. As a result of antibiotic treatment, favorable outcomes were confirmed by improving clinical symptoms and follow-up chest CT scans. A close combination of pulmonary symptoms, peripheral blood eosinophilia, abnormal chest imaging, and histopathological findings must be taken to confirm the diagnosis of Loeffler's syndrome.Kiem Hao Tran, A/Prof, PhDKim Hoa Nguyen-Thi, MDNguyen Cuong Pham, MD, PhDCong Thuan Dang, MD, PhDElsevierarticleLoeffler's syndromeEosinophiliaChest radiographComputed tomographyMedical physics. Medical radiology. Nuclear medicineR895-920ENRadiology Case Reports, Vol 17, Iss 1, Pp 245-249 (2022)
institution	DOAJ
collection	DOAJ
language	EN
topic	Loeffler's syndrome Eosinophilia Chest radiograph Computed tomography Medical physics. Medical radiology. Nuclear medicine R895-920
spellingShingle	Loeffler's syndrome Eosinophilia Chest radiograph Computed tomography Medical physics. Medical radiology. Nuclear medicine R895-920 Kiem Hao Tran, A/Prof, PhD Kim Hoa Nguyen-Thi, MD Nguyen Cuong Pham, MD, PhD Cong Thuan Dang, MD, PhD Loeffler's syndrome in a child: A rare radiological and histopathological diagnosis
description	Loffler syndrome is an uncommon, self-limited, benign pulmonary eosinophilia that usually lasts less than a month. Abnormal chest radiography occurs in 95% of patients; however, computed tomography findings are not well described. We present clinical features, radiological, and pathological findings of Loeffler's syndrome with secondary bacterial pneumonia in a child. He presented with dry cough, hemoptysis 2 times, chest pain for 1 week. Blood tests revealed high C-reactive protein levels and eosinophilia. On the initial computed tomography (CT) scan, a lesion was discovered at the upper edge of the right lung hilum. The lesion developed in size, together with right pleural effusion, on the repeated CT scan. A lung biopsy revealed a substantial number of inflammatory cells, including eosinophils and neutrophils. After ruling all other possibilities, Loffler's syndrome was confirmed. As a result of antibiotic treatment, favorable outcomes were confirmed by improving clinical symptoms and follow-up chest CT scans. A close combination of pulmonary symptoms, peripheral blood eosinophilia, abnormal chest imaging, and histopathological findings must be taken to confirm the diagnosis of Loeffler's syndrome.
format	article
author	Kiem Hao Tran, A/Prof, PhD Kim Hoa Nguyen-Thi, MD Nguyen Cuong Pham, MD, PhD Cong Thuan Dang, MD, PhD
author_facet	Kiem Hao Tran, A/Prof, PhD Kim Hoa Nguyen-Thi, MD Nguyen Cuong Pham, MD, PhD Cong Thuan Dang, MD, PhD
author_sort	Kiem Hao Tran, A/Prof, PhD
title	Loeffler's syndrome in a child: A rare radiological and histopathological diagnosis
title_short	Loeffler's syndrome in a child: A rare radiological and histopathological diagnosis
title_full	Loeffler's syndrome in a child: A rare radiological and histopathological diagnosis
title_fullStr	Loeffler's syndrome in a child: A rare radiological and histopathological diagnosis
title_full_unstemmed	Loeffler's syndrome in a child: A rare radiological and histopathological diagnosis
title_sort	loeffler's syndrome in a child: a rare radiological and histopathological diagnosis
publisher	Elsevier
publishDate	2022
url	https://doaj.org/article/221827ac28174caba38a49d77b511f80
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_version_	1718406791726891008

Loeffler's syndrome in a child: A rare radiological and histopathological diagnosis

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