Global mapping of CARM1 substrates defines enzyme specificity and substrate recognition
Arginine methylation is an abundant post-translational modification catalysed by protein arginine methyltransferases (PRMTs). Here the authors use quantitative mass spectrometry to globally profile the substrates of the PRMT CARM1 in breast cancer cells, and establish a role for CARM1’s N-terminus i...
Guardado en:
Autores principales: | Evgenia Shishkova, Hao Zeng, Fabao Liu, Nicholas W. Kwiecien, Alexander S. Hebert, Joshua J. Coon, Wei Xu |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/222565a41f79486c861ca88378e98eac |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Insights into substrate recognition and specificity for IgG by Endoglycosidase S2.
por: Asaminew H Aytenfisu, et al.
Publicado: (2021) -
Single-mutation fitness landscapes for an enzyme on multiple substrates reveal specificity is globally encoded
por: Emily E. Wrenbeck, et al.
Publicado: (2017) -
On the optimality of the enzyme-substrate relationship in bacteria.
por: Hugo Dourado, et al.
Publicado: (2021) -
On the optimality of the enzyme–substrate relationship in bacteria
por: Hugo Dourado, et al.
Publicado: (2021) -
Assembly and substrate recognition of curli biogenesis system
por: Zhaofeng Yan, et al.
Publicado: (2020)