Tight nanoscale clustering of Fcγ receptors using DNA origami promotes phagocytosis
Macrophages destroy pathogens and diseased cells through Fcγ receptor (FcγR)-driven phagocytosis of antibody-opsonized targets. Phagocytosis requires activation of multiple FcγRs, but the mechanism controlling the threshold for response is unclear. We developed a DNA origami-based engulfment system...
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| Auteurs principaux: | , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
eLife Sciences Publications Ltd
2021
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/22326acb213c44e0bb2e15c5800764e0 |
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