Staphylococcal phages and pathogenicity islands drive plasmid evolution

Many plasmids can be transferred between bacterial cells via conjugation; however, the mechanisms underlying the transfer of non-conjugative plasmids are less clear. Here, Humphrey et al. show that staphylococcal phages and a family of pathogenicity islands (PICIs) can mediate intra- and inter-speci...

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Autores principales: Suzanne Humphrey, Álvaro San Millán, Macarena Toll-Riera, John Connolly, Alejandra Flor-Duro, John Chen, Carles Ubeda, R. Craig MacLean, José R. Penadés
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/223838baccfd4b7e90e35bc7462be767
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spelling oai:doaj.org-article:223838baccfd4b7e90e35bc7462be7672021-12-02T19:16:20ZStaphylococcal phages and pathogenicity islands drive plasmid evolution10.1038/s41467-021-26101-52041-1723https://doaj.org/article/223838baccfd4b7e90e35bc7462be7672021-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26101-5https://doaj.org/toc/2041-1723Many plasmids can be transferred between bacterial cells via conjugation; however, the mechanisms underlying the transfer of non-conjugative plasmids are less clear. Here, Humphrey et al. show that staphylococcal phages and a family of pathogenicity islands (PICIs) can mediate intra- and inter-species plasmid transfer via generalised transduction.Suzanne HumphreyÁlvaro San MillánMacarena Toll-RieraJohn ConnollyAlejandra Flor-DuroJohn ChenCarles UbedaR. Craig MacLeanJosé R. PenadésNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Suzanne Humphrey
Álvaro San Millán
Macarena Toll-Riera
John Connolly
Alejandra Flor-Duro
John Chen
Carles Ubeda
R. Craig MacLean
José R. Penadés
Staphylococcal phages and pathogenicity islands drive plasmid evolution
description Many plasmids can be transferred between bacterial cells via conjugation; however, the mechanisms underlying the transfer of non-conjugative plasmids are less clear. Here, Humphrey et al. show that staphylococcal phages and a family of pathogenicity islands (PICIs) can mediate intra- and inter-species plasmid transfer via generalised transduction.
format article
author Suzanne Humphrey
Álvaro San Millán
Macarena Toll-Riera
John Connolly
Alejandra Flor-Duro
John Chen
Carles Ubeda
R. Craig MacLean
José R. Penadés
author_facet Suzanne Humphrey
Álvaro San Millán
Macarena Toll-Riera
John Connolly
Alejandra Flor-Duro
John Chen
Carles Ubeda
R. Craig MacLean
José R. Penadés
author_sort Suzanne Humphrey
title Staphylococcal phages and pathogenicity islands drive plasmid evolution
title_short Staphylococcal phages and pathogenicity islands drive plasmid evolution
title_full Staphylococcal phages and pathogenicity islands drive plasmid evolution
title_fullStr Staphylococcal phages and pathogenicity islands drive plasmid evolution
title_full_unstemmed Staphylococcal phages and pathogenicity islands drive plasmid evolution
title_sort staphylococcal phages and pathogenicity islands drive plasmid evolution
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/223838baccfd4b7e90e35bc7462be767
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