<italic toggle="yes">De Novo</italic> Generation of a Unique Cervid Prion Strain Using Protein Misfolding Cyclic Amplification

<italic toggle="yes">De Novo</italic> Generation of a Unique Cervid Prion Strain Using Protein Misfolding Cyclic Amplification

ABSTRACT Substantial evidence supports the hypothesis that prions are misfolded, infectious, insoluble, and protease-resistant proteins (PrPRES) devoid of instructional nucleic acid that cause transmissible spongiform encephalopathies (TSEs). Protein misfolding cyclic amplification (PMCA) has provid...

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Autores principales: Crystal Meyerett-Reid, A. Christy Wyckoff, Terry Spraker, Bruce Pulford, Heather Bender, Mark D. Zabel
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
Materias:
chronic wasting disease
prions
protein misfolding cyclic amplification
spontaneous generation
strains
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/223966d16ccb44c693a8127d11af7d11
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