Dual stem cell therapy synergistically improves cardiac function and vascular regeneration following myocardial infarction

Myocardial infarction causes damage to the myocardium and vasculature. Here the authors show in a rat model of myocardial infarction that cardiomyocytes derived from human induced pluripotent stem cells combined with a human mesenchymal stem cell-loaded patch lead to improved cardiac function and pr...

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Autores principales: Soon-Jung Park, Ri Youn Kim, Bong-Woo Park, Sunghun Lee, Seong Woo Choi, Jae-Hyun Park, Jong Jin Choi, Seok-Won Kim, Jinah Jang, Dong-Woo Cho, Hyung-Min Chung, Sung-Hwan Moon, Kiwon Ban, Hun-Jun Park
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/224681cc4e484c57ae1ce177be1472bc
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Sumario:Myocardial infarction causes damage to the myocardium and vasculature. Here the authors show in a rat model of myocardial infarction that cardiomyocytes derived from human induced pluripotent stem cells combined with a human mesenchymal stem cell-loaded patch lead to improved cardiac function and promote vessel formation.