Dual stem cell therapy synergistically improves cardiac function and vascular regeneration following myocardial infarction

Myocardial infarction causes damage to the myocardium and vasculature. Here the authors show in a rat model of myocardial infarction that cardiomyocytes derived from human induced pluripotent stem cells combined with a human mesenchymal stem cell-loaded patch lead to improved cardiac function and pr...

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Autores principales: Soon-Jung Park, Ri Youn Kim, Bong-Woo Park, Sunghun Lee, Seong Woo Choi, Jae-Hyun Park, Jong Jin Choi, Seok-Won Kim, Jinah Jang, Dong-Woo Cho, Hyung-Min Chung, Sung-Hwan Moon, Kiwon Ban, Hun-Jun Park
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/224681cc4e484c57ae1ce177be1472bc
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spelling oai:doaj.org-article:224681cc4e484c57ae1ce177be1472bc2021-12-02T14:38:57ZDual stem cell therapy synergistically improves cardiac function and vascular regeneration following myocardial infarction10.1038/s41467-019-11091-22041-1723https://doaj.org/article/224681cc4e484c57ae1ce177be1472bc2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11091-2https://doaj.org/toc/2041-1723Myocardial infarction causes damage to the myocardium and vasculature. Here the authors show in a rat model of myocardial infarction that cardiomyocytes derived from human induced pluripotent stem cells combined with a human mesenchymal stem cell-loaded patch lead to improved cardiac function and promote vessel formation.Soon-Jung ParkRi Youn KimBong-Woo ParkSunghun LeeSeong Woo ChoiJae-Hyun ParkJong Jin ChoiSeok-Won KimJinah JangDong-Woo ChoHyung-Min ChungSung-Hwan MoonKiwon BanHun-Jun ParkNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Soon-Jung Park
Ri Youn Kim
Bong-Woo Park
Sunghun Lee
Seong Woo Choi
Jae-Hyun Park
Jong Jin Choi
Seok-Won Kim
Jinah Jang
Dong-Woo Cho
Hyung-Min Chung
Sung-Hwan Moon
Kiwon Ban
Hun-Jun Park
Dual stem cell therapy synergistically improves cardiac function and vascular regeneration following myocardial infarction
description Myocardial infarction causes damage to the myocardium and vasculature. Here the authors show in a rat model of myocardial infarction that cardiomyocytes derived from human induced pluripotent stem cells combined with a human mesenchymal stem cell-loaded patch lead to improved cardiac function and promote vessel formation.
format article
author Soon-Jung Park
Ri Youn Kim
Bong-Woo Park
Sunghun Lee
Seong Woo Choi
Jae-Hyun Park
Jong Jin Choi
Seok-Won Kim
Jinah Jang
Dong-Woo Cho
Hyung-Min Chung
Sung-Hwan Moon
Kiwon Ban
Hun-Jun Park
author_facet Soon-Jung Park
Ri Youn Kim
Bong-Woo Park
Sunghun Lee
Seong Woo Choi
Jae-Hyun Park
Jong Jin Choi
Seok-Won Kim
Jinah Jang
Dong-Woo Cho
Hyung-Min Chung
Sung-Hwan Moon
Kiwon Ban
Hun-Jun Park
author_sort Soon-Jung Park
title Dual stem cell therapy synergistically improves cardiac function and vascular regeneration following myocardial infarction
title_short Dual stem cell therapy synergistically improves cardiac function and vascular regeneration following myocardial infarction
title_full Dual stem cell therapy synergistically improves cardiac function and vascular regeneration following myocardial infarction
title_fullStr Dual stem cell therapy synergistically improves cardiac function and vascular regeneration following myocardial infarction
title_full_unstemmed Dual stem cell therapy synergistically improves cardiac function and vascular regeneration following myocardial infarction
title_sort dual stem cell therapy synergistically improves cardiac function and vascular regeneration following myocardial infarction
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/224681cc4e484c57ae1ce177be1472bc
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