miRNA142-3p targets Tet2 and impairs Treg differentiation and stability in models of type 1 diabetes

miRNA142-3p targets Tet2 and impairs Treg differentiation and stability in models of type 1 diabetes

miRNA142-3p and Tet2 are separately known to regulate Treg. Here the authors show that miRNA142-3p targets Tet2 and by this opposes Treg differentiation in autoimmune diabetes.

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Detalles Bibliográficos
Autores principales: Martin G. Scherm, Isabelle Serr, Adam M. Zahm, Jonathan Schug, Saverio Bellusci, Rossella Manfredini, Victoria K. Salb, Katharina Gerlach, Benno Weigmann, Anette-Gabriele Ziegler, Klaus H. Kaestner, Carolin Daniel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/224be2193f454379b9efe6527272f625
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https://doaj.org/article/224be2193f454379b9efe6527272f625

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