Reconstructing the evolutionary history of pandemic foot-and-mouth disease viruses: the impact of recombination within the emerging O/ME-SA/Ind-2001 lineage
Abstract Foot-and-mouth disease (FMD) is a highly contagious disease of livestock affecting animal production and trade throughout Asia and Africa. Understanding FMD virus (FMDV) global movements and evolution can help to reconstruct the disease spread between endemic regions and predict the risks o...
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2018
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/224c0f250fc44985bb9c33860a396cf8 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:224c0f250fc44985bb9c33860a396cf8 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:224c0f250fc44985bb9c33860a396cf82021-12-02T15:09:03ZReconstructing the evolutionary history of pandemic foot-and-mouth disease viruses: the impact of recombination within the emerging O/ME-SA/Ind-2001 lineage10.1038/s41598-018-32693-82045-2322https://doaj.org/article/224c0f250fc44985bb9c33860a396cf82018-10-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-32693-8https://doaj.org/toc/2045-2322Abstract Foot-and-mouth disease (FMD) is a highly contagious disease of livestock affecting animal production and trade throughout Asia and Africa. Understanding FMD virus (FMDV) global movements and evolution can help to reconstruct the disease spread between endemic regions and predict the risks of incursion into FMD-free countries. Global expansion of a single FMDV lineage is rare but can result in severe economic consequences. Using extensive sequence data we have reconstructed the global space-time transmission history of the O/ME-SA/Ind-2001 lineage (which normally circulates in the Indian sub-continent) providing evidence of at least 15 independent escapes during 2013–2017 that have led to outbreaks in North Africa, the Middle East, Southeast Asia, the Far East and the FMD-free islands of Mauritius. We demonstrated that sequence heterogeneity of this emerging FMDV lineage is accommodated within two co-evolving divergent sublineages and that recombination by exchange of capsid-coding sequences can impact upon the reconstructed evolutionary histories. Thus, we recommend that only sequences encoding the outer capsid proteins should be used for broad-scale phylogeographical reconstruction. These data emphasise the importance of the Indian subcontinent as a source of FMDV that can spread across large distances and illustrates the impact of FMDV genome recombination on FMDV molecular epidemiology.Katarzyna Bachanek-BankowskaAntonello Di NardoJemma WadsworthValerie MiouletGiulia PezzoniSantina GrazioliEmiliana BrocchiSharmila Chapagain KafleRanjani HettiarachchiPradeep Lakpriya KumarawaduIbrahim M. EldaghayesAbdunaser S. DayhumDeodass MeenowaSoufien SghaierHafsa MadaniNabil AbouchoaibBui Huy HoangPham Phong VuKinzang DukpaRatna Bahadur GurungSangay TenzinUlrich WerneryAlongkorn PanthumartKingkarn Boonsuya SeeyoWilai LinchongsubongkochAnthony RelmyLabib Bakkali-KassimiAlexei ScherbakovDonald P. KingNick J. KnowlesNature PortfolioarticleFMD Virus (FMDV)SublinesIndian SubcontinentMost Recent Common Ancestor (MRCA)Markovian JumpMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-11 (2018) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
FMD Virus (FMDV) Sublines Indian Subcontinent Most Recent Common Ancestor (MRCA) Markovian Jump Medicine R Science Q |
| spellingShingle |
FMD Virus (FMDV) Sublines Indian Subcontinent Most Recent Common Ancestor (MRCA) Markovian Jump Medicine R Science Q Katarzyna Bachanek-Bankowska Antonello Di Nardo Jemma Wadsworth Valerie Mioulet Giulia Pezzoni Santina Grazioli Emiliana Brocchi Sharmila Chapagain Kafle Ranjani Hettiarachchi Pradeep Lakpriya Kumarawadu Ibrahim M. Eldaghayes Abdunaser S. Dayhum Deodass Meenowa Soufien Sghaier Hafsa Madani Nabil Abouchoaib Bui Huy Hoang Pham Phong Vu Kinzang Dukpa Ratna Bahadur Gurung Sangay Tenzin Ulrich Wernery Alongkorn Panthumart Kingkarn Boonsuya Seeyo Wilai Linchongsubongkoch Anthony Relmy Labib Bakkali-Kassimi Alexei Scherbakov Donald P. King Nick J. Knowles Reconstructing the evolutionary history of pandemic foot-and-mouth disease viruses: the impact of recombination within the emerging O/ME-SA/Ind-2001 lineage |
| description |
Abstract Foot-and-mouth disease (FMD) is a highly contagious disease of livestock affecting animal production and trade throughout Asia and Africa. Understanding FMD virus (FMDV) global movements and evolution can help to reconstruct the disease spread between endemic regions and predict the risks of incursion into FMD-free countries. Global expansion of a single FMDV lineage is rare but can result in severe economic consequences. Using extensive sequence data we have reconstructed the global space-time transmission history of the O/ME-SA/Ind-2001 lineage (which normally circulates in the Indian sub-continent) providing evidence of at least 15 independent escapes during 2013–2017 that have led to outbreaks in North Africa, the Middle East, Southeast Asia, the Far East and the FMD-free islands of Mauritius. We demonstrated that sequence heterogeneity of this emerging FMDV lineage is accommodated within two co-evolving divergent sublineages and that recombination by exchange of capsid-coding sequences can impact upon the reconstructed evolutionary histories. Thus, we recommend that only sequences encoding the outer capsid proteins should be used for broad-scale phylogeographical reconstruction. These data emphasise the importance of the Indian subcontinent as a source of FMDV that can spread across large distances and illustrates the impact of FMDV genome recombination on FMDV molecular epidemiology. |
| format |
article |
| author |
Katarzyna Bachanek-Bankowska Antonello Di Nardo Jemma Wadsworth Valerie Mioulet Giulia Pezzoni Santina Grazioli Emiliana Brocchi Sharmila Chapagain Kafle Ranjani Hettiarachchi Pradeep Lakpriya Kumarawadu Ibrahim M. Eldaghayes Abdunaser S. Dayhum Deodass Meenowa Soufien Sghaier Hafsa Madani Nabil Abouchoaib Bui Huy Hoang Pham Phong Vu Kinzang Dukpa Ratna Bahadur Gurung Sangay Tenzin Ulrich Wernery Alongkorn Panthumart Kingkarn Boonsuya Seeyo Wilai Linchongsubongkoch Anthony Relmy Labib Bakkali-Kassimi Alexei Scherbakov Donald P. King Nick J. Knowles |
| author_facet |
Katarzyna Bachanek-Bankowska Antonello Di Nardo Jemma Wadsworth Valerie Mioulet Giulia Pezzoni Santina Grazioli Emiliana Brocchi Sharmila Chapagain Kafle Ranjani Hettiarachchi Pradeep Lakpriya Kumarawadu Ibrahim M. Eldaghayes Abdunaser S. Dayhum Deodass Meenowa Soufien Sghaier Hafsa Madani Nabil Abouchoaib Bui Huy Hoang Pham Phong Vu Kinzang Dukpa Ratna Bahadur Gurung Sangay Tenzin Ulrich Wernery Alongkorn Panthumart Kingkarn Boonsuya Seeyo Wilai Linchongsubongkoch Anthony Relmy Labib Bakkali-Kassimi Alexei Scherbakov Donald P. King Nick J. Knowles |
| author_sort |
Katarzyna Bachanek-Bankowska |
| title |
Reconstructing the evolutionary history of pandemic foot-and-mouth disease viruses: the impact of recombination within the emerging O/ME-SA/Ind-2001 lineage |
| title_short |
Reconstructing the evolutionary history of pandemic foot-and-mouth disease viruses: the impact of recombination within the emerging O/ME-SA/Ind-2001 lineage |
| title_full |
Reconstructing the evolutionary history of pandemic foot-and-mouth disease viruses: the impact of recombination within the emerging O/ME-SA/Ind-2001 lineage |
| title_fullStr |
Reconstructing the evolutionary history of pandemic foot-and-mouth disease viruses: the impact of recombination within the emerging O/ME-SA/Ind-2001 lineage |
| title_full_unstemmed |
Reconstructing the evolutionary history of pandemic foot-and-mouth disease viruses: the impact of recombination within the emerging O/ME-SA/Ind-2001 lineage |
| title_sort |
reconstructing the evolutionary history of pandemic foot-and-mouth disease viruses: the impact of recombination within the emerging o/me-sa/ind-2001 lineage |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/224c0f250fc44985bb9c33860a396cf8 |
| work_keys_str_mv |
AT katarzynabachanekbankowska reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT antonellodinardo reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT jemmawadsworth reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT valeriemioulet reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT giuliapezzoni reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT santinagrazioli reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT emilianabrocchi reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT sharmilachapagainkafle reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT ranjanihettiarachchi reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT pradeeplakpriyakumarawadu reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT ibrahimmeldaghayes reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT abdunasersdayhum reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT deodassmeenowa reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT soufiensghaier reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT hafsamadani reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT nabilabouchoaib reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT buihuyhoang reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT phamphongvu reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT kinzangdukpa reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT ratnabahadurgurung reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT sangaytenzin reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT ulrichwernery reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT alongkornpanthumart reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT kingkarnboonsuyaseeyo reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT wilailinchongsubongkoch reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT anthonyrelmy reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT labibbakkalikassimi reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT alexeischerbakov reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT donaldpking reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage AT nickjknowles reconstructingtheevolutionaryhistoryofpandemicfootandmouthdiseasevirusestheimpactofrecombinationwithintheemergingomesaind2001lineage |
| _version_ |
1718387926142812160 |