Complement C5 is not critical for the formation of sub-RPE deposits in Efemp1 mutant mice

Complement C5 is not critical for the formation of sub-RPE deposits in Efemp1 mutant mice

Abstract The complement system plays a role in the formation of sub-retinal pigment epithelial (RPE) deposits in early stages of age-related macular degeneration (AMD). But the specific mechanisms that connect complement activation and deposit formation in AMD patients are unknown, which limits the...

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Autores principales: Donita L. Garland, Eric A. Pierce, Rosario Fernandez-Godino
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/2259019cd6ae4e0484dfbf83b812201a
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