Thermodynamic control of −1 programmed ribosomal frameshifting

Programmed ribosomal frameshifting (PRF) is an alternative translation strategy that causes controlled slippage of the ribosome along the mRNA, changing the sequence of the synthesized protein. Here the authors provide a thermodynamic framework that explains how mRNA sequence determines the efficien...

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Autores principales:	Lars V. Bock, Neva Caliskan, Natalia Korniy, Frank Peske, Marina V. Rodnina, Helmut Grubmüller
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/227669040cf540618b30da976bf14062
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spelling	oai:doaj.org-article:227669040cf540618b30da976bf140622021-12-02T15:35:51ZThermodynamic control of −1 programmed ribosomal frameshifting10.1038/s41467-019-12648-x2041-1723https://doaj.org/article/227669040cf540618b30da976bf140622019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12648-xhttps://doaj.org/toc/2041-1723Programmed ribosomal frameshifting (PRF) is an alternative translation strategy that causes controlled slippage of the ribosome along the mRNA, changing the sequence of the synthesized protein. Here the authors provide a thermodynamic framework that explains how mRNA sequence determines the efficiency of frameshifting.Lars V. BockNeva CaliskanNatalia KorniyFrank PeskeMarina V. RodninaHelmut GrubmüllerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lars V. Bock Neva Caliskan Natalia Korniy Frank Peske Marina V. Rodnina Helmut Grubmüller Thermodynamic control of −1 programmed ribosomal frameshifting
description	Programmed ribosomal frameshifting (PRF) is an alternative translation strategy that causes controlled slippage of the ribosome along the mRNA, changing the sequence of the synthesized protein. Here the authors provide a thermodynamic framework that explains how mRNA sequence determines the efficiency of frameshifting.
format	article
author	Lars V. Bock Neva Caliskan Natalia Korniy Frank Peske Marina V. Rodnina Helmut Grubmüller
author_facet	Lars V. Bock Neva Caliskan Natalia Korniy Frank Peske Marina V. Rodnina Helmut Grubmüller
author_sort	Lars V. Bock
title	Thermodynamic control of −1 programmed ribosomal frameshifting
title_short	Thermodynamic control of −1 programmed ribosomal frameshifting
title_full	Thermodynamic control of −1 programmed ribosomal frameshifting
title_fullStr	Thermodynamic control of −1 programmed ribosomal frameshifting
title_full_unstemmed	Thermodynamic control of −1 programmed ribosomal frameshifting
title_sort	thermodynamic control of −1 programmed ribosomal frameshifting
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/227669040cf540618b30da976bf14062
work_keys_str_mv	AT larsvbock thermodynamiccontrolof1programmedribosomalframeshifting AT nevacaliskan thermodynamiccontrolof1programmedribosomalframeshifting AT nataliakorniy thermodynamiccontrolof1programmedribosomalframeshifting AT frankpeske thermodynamiccontrolof1programmedribosomalframeshifting AT marinavrodnina thermodynamiccontrolof1programmedribosomalframeshifting AT helmutgrubmuller thermodynamiccontrolof1programmedribosomalframeshifting
_version_	1718386400086196224

Thermodynamic control of −1 programmed ribosomal frameshifting

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