Thermodynamic control of −1 programmed ribosomal frameshifting

Thermodynamic control of −1 programmed ribosomal frameshifting

Programmed ribosomal frameshifting (PRF) is an alternative translation strategy that causes controlled slippage of the ribosome along the mRNA, changing the sequence of the synthesized protein. Here the authors provide a thermodynamic framework that explains how mRNA sequence determines the efficien...

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Autores principales: Lars V. Bock, Neva Caliskan, Natalia Korniy, Frank Peske, Marina V. Rodnina, Helmut Grubmüller
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/227669040cf540618b30da976bf14062
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