Measles antibody seropositivity among children with allergic diseases: A cross-sectional study in the Japan Environment & Children's Pilot Study.

<h4>Background</h4>The relationship between allergic individuals and their responsiveness to routine vaccines has rarely been investigated. This study examined whether the seroprevalence of measles antibody differed between children with and without allergic diseases in the general pedia...

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Autores principales: Mayako Saito-Abe, Kiwako Yamamoto-Hanada, Kensuke Shoji, Miori Sato, Makoto Irahara, Yu Taniguchi, Makiko Sekiyama, Nathan Mise, Akihiko Ikegami, Masayuki Shimono, Reiko Suga, Masafumi Sanefuji, Shouichi Ohga, Masako Oda, Hiroshi Mitsubuchi, Isao Miyairi, Yukihiro Ohya
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Publicado: Public Library of Science (PLoS) 2021
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spelling oai:doaj.org-article:227d857f483d4b8294e6d7affc085db12021-12-02T20:08:06ZMeasles antibody seropositivity among children with allergic diseases: A cross-sectional study in the Japan Environment & Children's Pilot Study.1932-620310.1371/journal.pone.0257721https://doaj.org/article/227d857f483d4b8294e6d7affc085db12021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0257721https://doaj.org/toc/1932-6203<h4>Background</h4>The relationship between allergic individuals and their responsiveness to routine vaccines has rarely been investigated. This study examined whether the seroprevalence of measles antibody differed between children with and without allergic diseases in the general pediatric population.<h4>Methods</h4>The cross-sectional study was performed within a prospective general birth cohort (a pilot study of the Japan Environment & Children's Pilot Study [JECS]) of children aged 8 years. The clinical history of allergic diseases, measles, and the concentration of measles immunoglobulin G titers in serum enzyme immunoassay were examined. Fisher's exact tests were used to assess the relationships between the allergic characteristics of the children and their measles antibody positivity rates.<h4>Results</h4>This study included 162 children. Any allergic disease was reported in 75 (46.3%). The measles antibody positivity rate was 94.7% among children with any allergic diseases and 92.0% among children without allergic diseases. Our results revealed no differences in measles antibody seropositivity between children with allergies and controls.<h4>Conclusions</h4>Children with allergies mount and maintain a comparable immune response to the measles vaccine.Mayako Saito-AbeKiwako Yamamoto-HanadaKensuke ShojiMiori SatoMakoto IraharaYu TaniguchiMakiko SekiyamaNathan MiseAkihiko IkegamiMasayuki ShimonoReiko SugaMasafumi SanefujiShouichi OhgaMasako OdaHiroshi MitsubuchiIsao MiyairiYukihiro OhyaPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 9, p e0257721 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Mayako Saito-Abe
Kiwako Yamamoto-Hanada
Kensuke Shoji
Miori Sato
Makoto Irahara
Yu Taniguchi
Makiko Sekiyama
Nathan Mise
Akihiko Ikegami
Masayuki Shimono
Reiko Suga
Masafumi Sanefuji
Shouichi Ohga
Masako Oda
Hiroshi Mitsubuchi
Isao Miyairi
Yukihiro Ohya
Measles antibody seropositivity among children with allergic diseases: A cross-sectional study in the Japan Environment & Children's Pilot Study.
description <h4>Background</h4>The relationship between allergic individuals and their responsiveness to routine vaccines has rarely been investigated. This study examined whether the seroprevalence of measles antibody differed between children with and without allergic diseases in the general pediatric population.<h4>Methods</h4>The cross-sectional study was performed within a prospective general birth cohort (a pilot study of the Japan Environment & Children's Pilot Study [JECS]) of children aged 8 years. The clinical history of allergic diseases, measles, and the concentration of measles immunoglobulin G titers in serum enzyme immunoassay were examined. Fisher's exact tests were used to assess the relationships between the allergic characteristics of the children and their measles antibody positivity rates.<h4>Results</h4>This study included 162 children. Any allergic disease was reported in 75 (46.3%). The measles antibody positivity rate was 94.7% among children with any allergic diseases and 92.0% among children without allergic diseases. Our results revealed no differences in measles antibody seropositivity between children with allergies and controls.<h4>Conclusions</h4>Children with allergies mount and maintain a comparable immune response to the measles vaccine.
format article
author Mayako Saito-Abe
Kiwako Yamamoto-Hanada
Kensuke Shoji
Miori Sato
Makoto Irahara
Yu Taniguchi
Makiko Sekiyama
Nathan Mise
Akihiko Ikegami
Masayuki Shimono
Reiko Suga
Masafumi Sanefuji
Shouichi Ohga
Masako Oda
Hiroshi Mitsubuchi
Isao Miyairi
Yukihiro Ohya
author_facet Mayako Saito-Abe
Kiwako Yamamoto-Hanada
Kensuke Shoji
Miori Sato
Makoto Irahara
Yu Taniguchi
Makiko Sekiyama
Nathan Mise
Akihiko Ikegami
Masayuki Shimono
Reiko Suga
Masafumi Sanefuji
Shouichi Ohga
Masako Oda
Hiroshi Mitsubuchi
Isao Miyairi
Yukihiro Ohya
author_sort Mayako Saito-Abe
title Measles antibody seropositivity among children with allergic diseases: A cross-sectional study in the Japan Environment & Children's Pilot Study.
title_short Measles antibody seropositivity among children with allergic diseases: A cross-sectional study in the Japan Environment & Children's Pilot Study.
title_full Measles antibody seropositivity among children with allergic diseases: A cross-sectional study in the Japan Environment & Children's Pilot Study.
title_fullStr Measles antibody seropositivity among children with allergic diseases: A cross-sectional study in the Japan Environment & Children's Pilot Study.
title_full_unstemmed Measles antibody seropositivity among children with allergic diseases: A cross-sectional study in the Japan Environment & Children's Pilot Study.
title_sort measles antibody seropositivity among children with allergic diseases: a cross-sectional study in the japan environment & children's pilot study.
publisher Public Library of Science (PLoS)
publishDate 2021
url https://doaj.org/article/227d857f483d4b8294e6d7affc085db1
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