Innate-like control of human iNKT cell autoreactivity via the hypervariable CDR3beta loop.

Innate-like control of human iNKT cell autoreactivity via the hypervariable CDR3beta loop.

Invariant Natural Killer T cells (iNKT) are a versatile lymphocyte subset with important roles in both host defense and immunological tolerance. They express a highly conserved TCR which mediates recognition of the non-polymorphic, lipid-binding molecule CD1d. The structure of human iNKT TCRs is uni...

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Detalles Bibliográficos
Autores principales: Gediminas Matulis, Joseph P Sanderson, Nikolai M Lissin, Maria B Asparuhova, Gopal R Bommineni, Daniel Schümperli, Richard R Schmidt, Peter M Villiger, Bent K Jakobsen, Stephan D Gadola
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/228093b8dfbf408ab4d907a528db008d
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