Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria

The C2 sulfonates taurine and isethionate are also present in the anaerobic mammalian gut, where they are converted into toxic H2S by sulfate and sulfite-reducing bacteria. Here the authors characterise the O2-sensitive enzyme IseG that catalyzes the C-S bond cleavage of isethionate and show that Is...

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Autores principales:	Meining Xing, Yifeng Wei, Yan Zhou, Jun Zhang, Lianyun Lin, Yiling Hu, Gaoqun Hua, Ankanahalli N. Nanjaraj Urs, Dazhi Liu, Feifei Wang, Cuixia Guo, Yang Tong, Mengya Li, Yanhong Liu, Ee Lui Ang, Huimin Zhao, Zhiguang Yuchi, Yan Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2282a632ed40415c96252d41aafc4d49
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spelling	oai:doaj.org-article:2282a632ed40415c96252d41aafc4d492021-12-02T14:40:20ZRadical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria10.1038/s41467-019-09618-82041-1723https://doaj.org/article/2282a632ed40415c96252d41aafc4d492019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09618-8https://doaj.org/toc/2041-1723The C2 sulfonates taurine and isethionate are also present in the anaerobic mammalian gut, where they are converted into toxic H2S by sulfate and sulfite-reducing bacteria. Here the authors characterise the O2-sensitive enzyme IseG that catalyzes the C-S bond cleavage of isethionate and show that IseG also plays a key role in converting taurine into H2S in Bilophila wadsworthia.Meining XingYifeng WeiYan ZhouJun ZhangLianyun LinYiling HuGaoqun HuaAnkanahalli N. Nanjaraj UrsDazhi LiuFeifei WangCuixia GuoYang TongMengya LiYanhong LiuEe Lui AngHuimin ZhaoZhiguang YuchiYan ZhangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Meining Xing Yifeng Wei Yan Zhou Jun Zhang Lianyun Lin Yiling Hu Gaoqun Hua Ankanahalli N. Nanjaraj Urs Dazhi Liu Feifei Wang Cuixia Guo Yang Tong Mengya Li Yanhong Liu Ee Lui Ang Huimin Zhao Zhiguang Yuchi Yan Zhang Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria
description	The C2 sulfonates taurine and isethionate are also present in the anaerobic mammalian gut, where they are converted into toxic H2S by sulfate and sulfite-reducing bacteria. Here the authors characterise the O2-sensitive enzyme IseG that catalyzes the C-S bond cleavage of isethionate and show that IseG also plays a key role in converting taurine into H2S in Bilophila wadsworthia.
format	article
author	Meining Xing Yifeng Wei Yan Zhou Jun Zhang Lianyun Lin Yiling Hu Gaoqun Hua Ankanahalli N. Nanjaraj Urs Dazhi Liu Feifei Wang Cuixia Guo Yang Tong Mengya Li Yanhong Liu Ee Lui Ang Huimin Zhao Zhiguang Yuchi Yan Zhang
author_facet	Meining Xing Yifeng Wei Yan Zhou Jun Zhang Lianyun Lin Yiling Hu Gaoqun Hua Ankanahalli N. Nanjaraj Urs Dazhi Liu Feifei Wang Cuixia Guo Yang Tong Mengya Li Yanhong Liu Ee Lui Ang Huimin Zhao Zhiguang Yuchi Yan Zhang
author_sort	Meining Xing
title	Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria
title_short	Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria
title_full	Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria
title_fullStr	Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria
title_full_unstemmed	Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria
title_sort	radical-mediated c-s bond cleavage in c2 sulfonate degradation by anaerobic bacteria
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/2282a632ed40415c96252d41aafc4d49
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Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria

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