Small hydrophobic protein of human metapneumovirus does not affect virus replication and host gene expression in vitro.

Small hydrophobic protein of human metapneumovirus does not affect virus replication and host gene expression in vitro.

Human metapneumovirus (HMPV) encodes a small hydrophobic (SH) protein of unknown function. HMPV from which the SH open reading frame was deleted (HMPVΔSH) was viable and displayed similar replication kinetics, cytopathic effect and plaque size compared with wild type HMPV in several cell-lines. In a...

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Autores principales: Miranda de Graaf, Sander Herfst, Jamil Aarbiou, Peter C Burgers, Fatiha Zaaraoui-Boutahar, Maarten Bijl, Wilfred van Ijcken, Eefje J A Schrauwen, Albert D M E Osterhaus, Theo M Luider, Bob J Scholte, Ron A M Fouchier, Arno C Andeweg
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/228aa1f0d2004a7998ff55e0cca15a17
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