Prevention and Treatment of Chemotherapy-Induced Alopecia

Background: Chemotherapy-induced alopecia (CIA) is one of the most dramatic side effects of chemotherapy. Currently no guidelines are available for its prevention and treatment. Several devices and drugs are used, but results are often disappointing. Aims: Our aim is to analyze drugs and devices...

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Autores principales: Alfredo Rossi, Gemma Caro, Maria Caterina Fortuna, Flavia Pigliacelli, Andrea D'Arino, Marta Carlesimo
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Lenguaje:EN
Publicado: Mattioli1885 2020
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Acceso en línea:https://doaj.org/article/2291325f80cd449db1e412933ce5c3c7
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spelling oai:doaj.org-article:2291325f80cd449db1e412933ce5c3c72021-11-17T08:28:37ZPrevention and Treatment of Chemotherapy-Induced Alopecia10.5826/dpc.1003a742160-9381https://doaj.org/article/2291325f80cd449db1e412933ce5c3c72020-06-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/1248https://doaj.org/toc/2160-9381 Background: Chemotherapy-induced alopecia (CIA) is one of the most dramatic side effects of chemotherapy. Currently no guidelines are available for its prevention and treatment. Several devices and drugs are used, but results are often disappointing. Aims: Our aim is to analyze drugs and devices proposed in the literature for prevention and treatment of CIA induced by cytotoxic drugs and to discuss the evidenced-based opinion. Methods and Results: Scalp cooling is the only agent that has been approved by the US Food and Drug Administration for CIA prevention. Minoxidil and bimatoprost should not be used during chemotherapy administration, but they can be used after chemotherapy discontinuation to obtain greater regrowth. Conclusions: Therapy should always be modulated for the patient and no fixed protocol should be used. Trichoscopy and trichogram could be useful tools in supporting this treatment. Alfredo RossiGemma CaroMaria Caterina FortunaFlavia PigliacelliAndrea D'ArinoMarta CarlesimoMattioli1885articlehair losschemotherapytreatmentalopeciaDermatologyRL1-803ENDermatology Practical & Conceptual, Vol 10, Iss 3 (2020)
institution DOAJ
collection DOAJ
language EN
topic hair loss
chemotherapy
treatment
alopecia
Dermatology
RL1-803
spellingShingle hair loss
chemotherapy
treatment
alopecia
Dermatology
RL1-803
Alfredo Rossi
Gemma Caro
Maria Caterina Fortuna
Flavia Pigliacelli
Andrea D'Arino
Marta Carlesimo
Prevention and Treatment of Chemotherapy-Induced Alopecia
description Background: Chemotherapy-induced alopecia (CIA) is one of the most dramatic side effects of chemotherapy. Currently no guidelines are available for its prevention and treatment. Several devices and drugs are used, but results are often disappointing. Aims: Our aim is to analyze drugs and devices proposed in the literature for prevention and treatment of CIA induced by cytotoxic drugs and to discuss the evidenced-based opinion. Methods and Results: Scalp cooling is the only agent that has been approved by the US Food and Drug Administration for CIA prevention. Minoxidil and bimatoprost should not be used during chemotherapy administration, but they can be used after chemotherapy discontinuation to obtain greater regrowth. Conclusions: Therapy should always be modulated for the patient and no fixed protocol should be used. Trichoscopy and trichogram could be useful tools in supporting this treatment.
format article
author Alfredo Rossi
Gemma Caro
Maria Caterina Fortuna
Flavia Pigliacelli
Andrea D'Arino
Marta Carlesimo
author_facet Alfredo Rossi
Gemma Caro
Maria Caterina Fortuna
Flavia Pigliacelli
Andrea D'Arino
Marta Carlesimo
author_sort Alfredo Rossi
title Prevention and Treatment of Chemotherapy-Induced Alopecia
title_short Prevention and Treatment of Chemotherapy-Induced Alopecia
title_full Prevention and Treatment of Chemotherapy-Induced Alopecia
title_fullStr Prevention and Treatment of Chemotherapy-Induced Alopecia
title_full_unstemmed Prevention and Treatment of Chemotherapy-Induced Alopecia
title_sort prevention and treatment of chemotherapy-induced alopecia
publisher Mattioli1885
publishDate 2020
url https://doaj.org/article/2291325f80cd449db1e412933ce5c3c7
work_keys_str_mv AT alfredorossi preventionandtreatmentofchemotherapyinducedalopecia
AT gemmacaro preventionandtreatmentofchemotherapyinducedalopecia
AT mariacaterinafortuna preventionandtreatmentofchemotherapyinducedalopecia
AT flaviapigliacelli preventionandtreatmentofchemotherapyinducedalopecia
AT andreadarino preventionandtreatmentofchemotherapyinducedalopecia
AT martacarlesimo preventionandtreatmentofchemotherapyinducedalopecia
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