Rationale and Strategies for Development of an Optimal Bundle of Management for Cardiac Arrest

Objectives:. To construct a highly detailed yet practical, attainable roadmap for enhancing the likelihood of neurologically intact survival following sudden cardiac arrest. Design, Setting, and Patients:. Population-based outcomes following out-of-hospital cardiac arrest were collated for 10 U.S. c...

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Autores principales: Paul E. Pepe, MD, MPH, MCCM, Tom P. Aufderheide, MD, MS, Lionel Lamhaut, MD, PhD, Daniel P. Davis, MD, Charles J. Lick, MD, Kees H. Polderman, MD, Kenneth A. Scheppke, MD, Charles D. Deakin, MD, Brian J. O’Neil, MD, Hans van Schuppen, MD, Michael K. Levy, MD, Marvin A. Wayne, MD, Scott T. Youngquist, MD, MS, Johanna C. Moore, MD, MS, Keith G. Lurie, MD, Jason A. Bartos, MD, PhD, Kerry M. Bachista, MD, EMT-P, Michael J. Jacobs, EMT-P, Carolina Rojas-Salvador, MD, Sean T. Grayson, MS, EMT-P, James E. Manning, MD, Michael C. Kurz, MD, Guillaume Debaty, MD, PhD, Nicolas Segal, MD, PhD, Peter M. Antevy, MD, David A. Miramontes, MD, Sheldon Cheskes, MD, Joseph E. Holley, MD, Ralph J. Frascone, MD, Raymond L. Fowler, MD, Demetris Yannopoulos, MD, on behalf of fellow International Resuscitation Collaborative Members, Paul E. Pepe, Tom P. Aufderheide, Lionel Lamhaut, Daniel P. Davis, Charles J. Lick, Kees H. Polderman, Kenneth A. Scheppke, Charles D. Deakin, Brian J. O’Neil, Hans van Schuppen, Michael K. Levy, Marvin A. Wayne, Scott T. Youngquist, Johanna C. Moore, Keith G. Lurie, Jason A. Bartos, Kerry M. Bachista, Michael J. Jacobs, Carolina Rojas-Salvador, Sean T. Grayson, James E. Manning, Michael C. Kurz, Guillaume Debaty, Nicolas Segal, Peter M. Antevy, David A. Miramontes, Sheldon Cheskes, Joseph E. Holley, Ralph J. Frascone, Brent Parquette, Raymond L. Fowler, Demetris Yannopoulos, Brent A. Parquette, Ganesh Raveendran, Alice Hutin, Renaud Tissier, Robert Niskanen, James H. Logan, Debbie Gillquist
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Publicado: Wolters Kluwer 2020
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collection DOAJ
language EN
topic Medical emergencies. Critical care. Intensive care. First aid
RC86-88.9
spellingShingle Medical emergencies. Critical care. Intensive care. First aid
RC86-88.9
Paul E. Pepe, MD, MPH, MCCM
Tom P. Aufderheide, MD, MS
Lionel Lamhaut, MD, PhD
Daniel P. Davis, MD
Charles J. Lick, MD
Kees H. Polderman, MD
Kenneth A. Scheppke, MD
Charles D. Deakin, MD
Brian J. O’Neil, MD
Hans van Schuppen, MD
Michael K. Levy, MD
Marvin A. Wayne, MD
Scott T. Youngquist, MD, MS
Johanna C. Moore, MD, MS
Keith G. Lurie, MD
Jason A. Bartos, MD, PhD
Kerry M. Bachista, MD, EMT-P
Michael J. Jacobs, EMT-P
Carolina Rojas-Salvador, MD
Sean T. Grayson, MS, EMT-P
James E. Manning, MD
Michael C. Kurz, MD
Guillaume Debaty, MD, PhD
Nicolas Segal, MD, PhD
Peter M. Antevy, MD
David A. Miramontes, MD
Sheldon Cheskes, MD
Joseph E. Holley, MD
Ralph J. Frascone, MD
Raymond L. Fowler, MD
Demetris Yannopoulos, MD
on behalf of fellow International Resuscitation Collaborative Members
Paul E. Pepe
Tom P. Aufderheide
Lionel Lamhaut
Daniel P. Davis
Charles J. Lick
Kees H. Polderman
Kenneth A. Scheppke
Charles D. Deakin
Brian J. O’Neil
Hans van Schuppen
Michael K. Levy
Marvin A. Wayne
Scott T. Youngquist
Johanna C. Moore
Keith G. Lurie
Jason A. Bartos
Kerry M. Bachista
Michael J. Jacobs
Carolina Rojas-Salvador
Sean T. Grayson
James E. Manning
Michael C. Kurz
Guillaume Debaty
Nicolas Segal
Peter M. Antevy
David A. Miramontes
Sheldon Cheskes
Joseph E. Holley
Ralph J. Frascone
Brent Parquette
Raymond L. Fowler
Demetris Yannopoulos
Brent A. Parquette
Ganesh Raveendran
Alice Hutin
Renaud Tissier
Robert Niskanen
James H. Logan
Debbie Gillquist
Rationale and Strategies for Development of an Optimal Bundle of Management for Cardiac Arrest
description Objectives:. To construct a highly detailed yet practical, attainable roadmap for enhancing the likelihood of neurologically intact survival following sudden cardiac arrest. Design, Setting, and Patients:. Population-based outcomes following out-of-hospital cardiac arrest were collated for 10 U.S. counties in Alaska, California, Florida, Ohio, Minnesota, Utah, and Washington. The 10 identified emergency medical services systems were those that had recently reported significant improvements in neurologically intact survival after introducing a more comprehensive approach involving citizens, hospitals, and evolving strategies for incorporating technology-based, highly choreographed care and training. Detailed inventories of in-common elements were collated from the ten 9-1-1 agencies and assimilated. For reference, combined averaged outcomes for out-of-hospital cardiac arrest occurring January 1, 2017, to February 28, 2018, were compared with concurrent U.S. outcomes reported by the well-established Cardiac Arrest Registry to Enhance Survival. Interventions:. Most commonly, interventions and components from the ten 9-1-1 systems consistently included extensive public cardiopulmonary resuscitation training, 9-1-1 system-connected smart phone applications, expedited dispatcher procedures, cardiopulmonary resuscitation quality monitoring, mechanical cardiopulmonary resuscitation, devices for enhancing negative intrathoracic pressure regulation, extracorporeal membrane oxygenation protocols, body temperature management procedures, rapid cardiac angiography, and intensive involvement of medical directors, operational and quality assurance officers, and training staff. Measurements and Main Results:. Compared with Cardiac Arrest Registry to Enhance Survival (n = 78,704), the cohorts from the 10 emergency medical services agencies examined (n = 2,911) demonstrated significantly increased likelihoods of return of spontaneous circulation (mean 37.4% vs 31.5%; p < 0.001) and neurologically favorable hospital discharge, particularly after witnessed collapses involving bystander cardiopulmonary resuscitation and shockable cardiac rhythms (mean 10.7% vs 8.4%; p < 0.001; and 41.6% vs 29.2%; p < 0.001, respectively). Conclusions:. The likelihood of neurologically favorable survival following out-of-hospital cardiac arrest can improve substantially in communities that conscientiously and meticulously introduce a well-sequenced, highly choreographed, system-wide portfolio of both traditional and nonconventional approaches to training, technologies, and physiologic management. The commonalities found in the analyzed systems create a compelling case that other communities can also improve out-of-hospital cardiac arrest outcomes significantly by conscientiously exploring and adopting similar bundles of system organization and care.
format article
author Paul E. Pepe, MD, MPH, MCCM
Tom P. Aufderheide, MD, MS
Lionel Lamhaut, MD, PhD
Daniel P. Davis, MD
Charles J. Lick, MD
Kees H. Polderman, MD
Kenneth A. Scheppke, MD
Charles D. Deakin, MD
Brian J. O’Neil, MD
Hans van Schuppen, MD
Michael K. Levy, MD
Marvin A. Wayne, MD
Scott T. Youngquist, MD, MS
Johanna C. Moore, MD, MS
Keith G. Lurie, MD
Jason A. Bartos, MD, PhD
Kerry M. Bachista, MD, EMT-P
Michael J. Jacobs, EMT-P
Carolina Rojas-Salvador, MD
Sean T. Grayson, MS, EMT-P
James E. Manning, MD
Michael C. Kurz, MD
Guillaume Debaty, MD, PhD
Nicolas Segal, MD, PhD
Peter M. Antevy, MD
David A. Miramontes, MD
Sheldon Cheskes, MD
Joseph E. Holley, MD
Ralph J. Frascone, MD
Raymond L. Fowler, MD
Demetris Yannopoulos, MD
on behalf of fellow International Resuscitation Collaborative Members
Paul E. Pepe
Tom P. Aufderheide
Lionel Lamhaut
Daniel P. Davis
Charles J. Lick
Kees H. Polderman
Kenneth A. Scheppke
Charles D. Deakin
Brian J. O’Neil
Hans van Schuppen
Michael K. Levy
Marvin A. Wayne
Scott T. Youngquist
Johanna C. Moore
Keith G. Lurie
Jason A. Bartos
Kerry M. Bachista
Michael J. Jacobs
Carolina Rojas-Salvador
Sean T. Grayson
James E. Manning
Michael C. Kurz
Guillaume Debaty
Nicolas Segal
Peter M. Antevy
David A. Miramontes
Sheldon Cheskes
Joseph E. Holley
Ralph J. Frascone
Brent Parquette
Raymond L. Fowler
Demetris Yannopoulos
Brent A. Parquette
Ganesh Raveendran
Alice Hutin
Renaud Tissier
Robert Niskanen
James H. Logan
Debbie Gillquist
author_facet Paul E. Pepe, MD, MPH, MCCM
Tom P. Aufderheide, MD, MS
Lionel Lamhaut, MD, PhD
Daniel P. Davis, MD
Charles J. Lick, MD
Kees H. Polderman, MD
Kenneth A. Scheppke, MD
Charles D. Deakin, MD
Brian J. O’Neil, MD
Hans van Schuppen, MD
Michael K. Levy, MD
Marvin A. Wayne, MD
Scott T. Youngquist, MD, MS
Johanna C. Moore, MD, MS
Keith G. Lurie, MD
Jason A. Bartos, MD, PhD
Kerry M. Bachista, MD, EMT-P
Michael J. Jacobs, EMT-P
Carolina Rojas-Salvador, MD
Sean T. Grayson, MS, EMT-P
James E. Manning, MD
Michael C. Kurz, MD
Guillaume Debaty, MD, PhD
Nicolas Segal, MD, PhD
Peter M. Antevy, MD
David A. Miramontes, MD
Sheldon Cheskes, MD
Joseph E. Holley, MD
Ralph J. Frascone, MD
Raymond L. Fowler, MD
Demetris Yannopoulos, MD
on behalf of fellow International Resuscitation Collaborative Members
Paul E. Pepe
Tom P. Aufderheide
Lionel Lamhaut
Daniel P. Davis
Charles J. Lick
Kees H. Polderman
Kenneth A. Scheppke
Charles D. Deakin
Brian J. O’Neil
Hans van Schuppen
Michael K. Levy
Marvin A. Wayne
Scott T. Youngquist
Johanna C. Moore
Keith G. Lurie
Jason A. Bartos
Kerry M. Bachista
Michael J. Jacobs
Carolina Rojas-Salvador
Sean T. Grayson
James E. Manning
Michael C. Kurz
Guillaume Debaty
Nicolas Segal
Peter M. Antevy
David A. Miramontes
Sheldon Cheskes
Joseph E. Holley
Ralph J. Frascone
Brent Parquette
Raymond L. Fowler
Demetris Yannopoulos
Brent A. Parquette
Ganesh Raveendran
Alice Hutin
Renaud Tissier
Robert Niskanen
James H. Logan
Debbie Gillquist
author_sort Paul E. Pepe, MD, MPH, MCCM
title Rationale and Strategies for Development of an Optimal Bundle of Management for Cardiac Arrest
title_short Rationale and Strategies for Development of an Optimal Bundle of Management for Cardiac Arrest
title_full Rationale and Strategies for Development of an Optimal Bundle of Management for Cardiac Arrest
title_fullStr Rationale and Strategies for Development of an Optimal Bundle of Management for Cardiac Arrest
title_full_unstemmed Rationale and Strategies for Development of an Optimal Bundle of Management for Cardiac Arrest
title_sort rationale and strategies for development of an optimal bundle of management for cardiac arrest
publisher Wolters Kluwer
publishDate 2020
url https://doaj.org/article/2293fcceaf264f8bb835c398f745db9d
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spelling oai:doaj.org-article:2293fcceaf264f8bb835c398f745db9d2021-11-25T07:52:32ZRationale and Strategies for Development of an Optimal Bundle of Management for Cardiac Arrest2639-802810.1097/CCE.0000000000000214https://doaj.org/article/2293fcceaf264f8bb835c398f745db9d2020-10-01T00:00:00Zhttp://journals.lww.com/10.1097/CCE.0000000000000214https://doaj.org/toc/2639-8028Objectives:. To construct a highly detailed yet practical, attainable roadmap for enhancing the likelihood of neurologically intact survival following sudden cardiac arrest. Design, Setting, and Patients:. Population-based outcomes following out-of-hospital cardiac arrest were collated for 10 U.S. counties in Alaska, California, Florida, Ohio, Minnesota, Utah, and Washington. The 10 identified emergency medical services systems were those that had recently reported significant improvements in neurologically intact survival after introducing a more comprehensive approach involving citizens, hospitals, and evolving strategies for incorporating technology-based, highly choreographed care and training. Detailed inventories of in-common elements were collated from the ten 9-1-1 agencies and assimilated. For reference, combined averaged outcomes for out-of-hospital cardiac arrest occurring January 1, 2017, to February 28, 2018, were compared with concurrent U.S. outcomes reported by the well-established Cardiac Arrest Registry to Enhance Survival. Interventions:. Most commonly, interventions and components from the ten 9-1-1 systems consistently included extensive public cardiopulmonary resuscitation training, 9-1-1 system-connected smart phone applications, expedited dispatcher procedures, cardiopulmonary resuscitation quality monitoring, mechanical cardiopulmonary resuscitation, devices for enhancing negative intrathoracic pressure regulation, extracorporeal membrane oxygenation protocols, body temperature management procedures, rapid cardiac angiography, and intensive involvement of medical directors, operational and quality assurance officers, and training staff. Measurements and Main Results:. Compared with Cardiac Arrest Registry to Enhance Survival (n = 78,704), the cohorts from the 10 emergency medical services agencies examined (n = 2,911) demonstrated significantly increased likelihoods of return of spontaneous circulation (mean 37.4% vs 31.5%; p < 0.001) and neurologically favorable hospital discharge, particularly after witnessed collapses involving bystander cardiopulmonary resuscitation and shockable cardiac rhythms (mean 10.7% vs 8.4%; p < 0.001; and 41.6% vs 29.2%; p < 0.001, respectively). Conclusions:. The likelihood of neurologically favorable survival following out-of-hospital cardiac arrest can improve substantially in communities that conscientiously and meticulously introduce a well-sequenced, highly choreographed, system-wide portfolio of both traditional and nonconventional approaches to training, technologies, and physiologic management. The commonalities found in the analyzed systems create a compelling case that other communities can also improve out-of-hospital cardiac arrest outcomes significantly by conscientiously exploring and adopting similar bundles of system organization and care.Paul E. Pepe, MD, MPH, MCCMTom P. Aufderheide, MD, MSLionel Lamhaut, MD, PhDDaniel P. Davis, MDCharles J. Lick, MDKees H. Polderman, MDKenneth A. Scheppke, MDCharles D. Deakin, MDBrian J. O’Neil, MDHans van Schuppen, MDMichael K. Levy, MDMarvin A. Wayne, MDScott T. Youngquist, MD, MSJohanna C. Moore, MD, MSKeith G. Lurie, MDJason A. Bartos, MD, PhDKerry M. Bachista, MD, EMT-PMichael J. Jacobs, EMT-PCarolina Rojas-Salvador, MDSean T. Grayson, MS, EMT-PJames E. Manning, MDMichael C. Kurz, MDGuillaume Debaty, MD, PhDNicolas Segal, MD, PhDPeter M. Antevy, MDDavid A. Miramontes, MDSheldon Cheskes, MDJoseph E. Holley, MDRalph J. Frascone, MDRaymond L. Fowler, MDDemetris Yannopoulos, MDon behalf of fellow International Resuscitation Collaborative MembersPaul E. PepeTom P. AufderheideLionel LamhautDaniel P. DavisCharles J. LickKees H. PoldermanKenneth A. ScheppkeCharles D. DeakinBrian J. O’NeilHans van SchuppenMichael K. LevyMarvin A. WayneScott T. YoungquistJohanna C. MooreKeith G. LurieJason A. BartosKerry M. BachistaMichael J. JacobsCarolina Rojas-SalvadorSean T. GraysonJames E. ManningMichael C. KurzGuillaume DebatyNicolas SegalPeter M. AntevyDavid A. MiramontesSheldon CheskesJoseph E. HolleyRalph J. FrasconeBrent ParquetteRaymond L. FowlerDemetris YannopoulosBrent A. ParquetteGanesh RaveendranAlice HutinRenaud TissierRobert NiskanenJames H. LoganDebbie GillquistWolters KluwerarticleMedical emergencies. Critical care. Intensive care. First aidRC86-88.9ENCritical Care Explorations, Vol 2, Iss 10, p e0214 (2020)