Electro-osmotic capture and ionic discrimination of peptide and protein biomarkers with FraC nanopores
Biological nanopore–based protein sequencing and recognition is challenging due to the folded structure or non-uniform charge of peptides. Here the authors show that engineered FraC nanopores can overcome these problems and recognize biomarkers in the form of oligopeptides, polypeptides and folded p...
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Autores principales: | Gang Huang, Kherim Willems, Misha Soskine, Carsten Wloka, Giovanni Maglia |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/229ceae5404f44ed83b8b5d44da50e41 |
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