The origin of heterogeneous nanoparticle uptake by cells

Cellular uptake of nanoparticles is highly variable between individual cells in a population. Here, the authors show that this heterogeneity is a result of varying numbers of nanoparticle-containing endosomes while the nanoparticle dose per endosome remains constant.

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Auteurs principaux:	Paul Rees, John W. Wills, M. Rowan Brown, Claire M. Barnes, Huw D. Summers
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2019
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/229f11f983af4f06a83137aaba5539e2
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id	oai:doaj.org-article:229f11f983af4f06a83137aaba5539e2
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spelling	oai:doaj.org-article:229f11f983af4f06a83137aaba5539e22021-12-02T16:57:20ZThe origin of heterogeneous nanoparticle uptake by cells10.1038/s41467-019-10112-42041-1723https://doaj.org/article/229f11f983af4f06a83137aaba5539e22019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10112-4https://doaj.org/toc/2041-1723Cellular uptake of nanoparticles is highly variable between individual cells in a population. Here, the authors show that this heterogeneity is a result of varying numbers of nanoparticle-containing endosomes while the nanoparticle dose per endosome remains constant.Paul ReesJohn W. WillsM. Rowan BrownClaire M. BarnesHuw D. SummersNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Paul Rees John W. Wills M. Rowan Brown Claire M. Barnes Huw D. Summers The origin of heterogeneous nanoparticle uptake by cells
description	Cellular uptake of nanoparticles is highly variable between individual cells in a population. Here, the authors show that this heterogeneity is a result of varying numbers of nanoparticle-containing endosomes while the nanoparticle dose per endosome remains constant.
format	article
author	Paul Rees John W. Wills M. Rowan Brown Claire M. Barnes Huw D. Summers
author_facet	Paul Rees John W. Wills M. Rowan Brown Claire M. Barnes Huw D. Summers
author_sort	Paul Rees
title	The origin of heterogeneous nanoparticle uptake by cells
title_short	The origin of heterogeneous nanoparticle uptake by cells
title_full	The origin of heterogeneous nanoparticle uptake by cells
title_fullStr	The origin of heterogeneous nanoparticle uptake by cells
title_full_unstemmed	The origin of heterogeneous nanoparticle uptake by cells
title_sort	origin of heterogeneous nanoparticle uptake by cells
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/229f11f983af4f06a83137aaba5539e2
work_keys_str_mv	AT paulrees theoriginofheterogeneousnanoparticleuptakebycells AT johnwwills theoriginofheterogeneousnanoparticleuptakebycells AT mrowanbrown theoriginofheterogeneousnanoparticleuptakebycells AT clairembarnes theoriginofheterogeneousnanoparticleuptakebycells AT huwdsummers theoriginofheterogeneousnanoparticleuptakebycells AT paulrees originofheterogeneousnanoparticleuptakebycells AT johnwwills originofheterogeneousnanoparticleuptakebycells AT mrowanbrown originofheterogeneousnanoparticleuptakebycells AT clairembarnes originofheterogeneousnanoparticleuptakebycells AT huwdsummers originofheterogeneousnanoparticleuptakebycells
_version_	1718382551212490752

The origin of heterogeneous nanoparticle uptake by cells

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