Identifying the rules of engagement enabling leukocyte rolling, activation, and adhesion.
The LFA-1 integrin plays a pivotal role in sustained leukocyte adhesion to the endothelial surface, which is a precondition for leukocyte recruitment into inflammation sites. Strong correlative evidence implicates LFA-1 clustering as being essential for sustained adhesion, and it may also facilitate...
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Auteurs principaux: | , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2010
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Accès en ligne: | https://doaj.org/article/22a4d59a9c8c47be815b35c7ff31fb5c |
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