First reported case of late recurrence of pulmonary mucormycosis in a renal transplant recipient with poorly controlled diabetes mellitus
Abstract Pulmonary mucormycosis (PM) is a rare, life‐threatening fungal infection usually affecting immunocompromised patients. Its incidence is rising, with a recent outbreak associated with COVID‐19 co‐infection. Amphotericin B along with early surgery are considered the standard treatment. Recurr...
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2021
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oai:doaj.org-article:22b1036d9b5540348bb5a5ece3e328562021-11-25T13:46:30ZFirst reported case of late recurrence of pulmonary mucormycosis in a renal transplant recipient with poorly controlled diabetes mellitus2051-338010.1002/rcr2.877https://doaj.org/article/22b1036d9b5540348bb5a5ece3e328562021-12-01T00:00:00Zhttps://doi.org/10.1002/rcr2.877https://doaj.org/toc/2051-3380Abstract Pulmonary mucormycosis (PM) is a rare, life‐threatening fungal infection usually affecting immunocompromised patients. Its incidence is rising, with a recent outbreak associated with COVID‐19 co‐infection. Amphotericin B along with early surgery are considered the standard treatment. Recurrence has been reported in patients without adequate treatment and without permanent reversal of predisposing factors. We report a case of late recurrence of PM in a renal transplant recipient. In 2012, he was diagnosed with PM. Imaging at the time showed a lingular mass. He was treated with antifungal for 1 year until complete radiological resolution. Surgical intervention was considered but no further follow‐up action was taken. In 2020, he presented with fever and haemoptysis. Imaging again showed a lingular mass, which was confirmed to be PM by bronchoscopic lung biopsy. This case highlights the importance of secondary antifungal prophylaxis for PM if permanent reversal of immunosuppression is not possible.Cheuk Cheung Derek LeungYu Hong ChanMan Ying HoMing Chiu ChanChun Hoi ChenChin Tong KwokYiu Cheong YeungWileyarticlediabetes mellituspulmonary mucormycosisrecurrencerenal transplantRhizopusDiseases of the respiratory systemRC705-779ENRespirology Case Reports, Vol 9, Iss 12, Pp n/a-n/a (2021) |
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diabetes mellitus pulmonary mucormycosis recurrence renal transplant Rhizopus Diseases of the respiratory system RC705-779 |
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diabetes mellitus pulmonary mucormycosis recurrence renal transplant Rhizopus Diseases of the respiratory system RC705-779 Cheuk Cheung Derek Leung Yu Hong Chan Man Ying Ho Ming Chiu Chan Chun Hoi Chen Chin Tong Kwok Yiu Cheong Yeung First reported case of late recurrence of pulmonary mucormycosis in a renal transplant recipient with poorly controlled diabetes mellitus |
description |
Abstract Pulmonary mucormycosis (PM) is a rare, life‐threatening fungal infection usually affecting immunocompromised patients. Its incidence is rising, with a recent outbreak associated with COVID‐19 co‐infection. Amphotericin B along with early surgery are considered the standard treatment. Recurrence has been reported in patients without adequate treatment and without permanent reversal of predisposing factors. We report a case of late recurrence of PM in a renal transplant recipient. In 2012, he was diagnosed with PM. Imaging at the time showed a lingular mass. He was treated with antifungal for 1 year until complete radiological resolution. Surgical intervention was considered but no further follow‐up action was taken. In 2020, he presented with fever and haemoptysis. Imaging again showed a lingular mass, which was confirmed to be PM by bronchoscopic lung biopsy. This case highlights the importance of secondary antifungal prophylaxis for PM if permanent reversal of immunosuppression is not possible. |
format |
article |
author |
Cheuk Cheung Derek Leung Yu Hong Chan Man Ying Ho Ming Chiu Chan Chun Hoi Chen Chin Tong Kwok Yiu Cheong Yeung |
author_facet |
Cheuk Cheung Derek Leung Yu Hong Chan Man Ying Ho Ming Chiu Chan Chun Hoi Chen Chin Tong Kwok Yiu Cheong Yeung |
author_sort |
Cheuk Cheung Derek Leung |
title |
First reported case of late recurrence of pulmonary mucormycosis in a renal transplant recipient with poorly controlled diabetes mellitus |
title_short |
First reported case of late recurrence of pulmonary mucormycosis in a renal transplant recipient with poorly controlled diabetes mellitus |
title_full |
First reported case of late recurrence of pulmonary mucormycosis in a renal transplant recipient with poorly controlled diabetes mellitus |
title_fullStr |
First reported case of late recurrence of pulmonary mucormycosis in a renal transplant recipient with poorly controlled diabetes mellitus |
title_full_unstemmed |
First reported case of late recurrence of pulmonary mucormycosis in a renal transplant recipient with poorly controlled diabetes mellitus |
title_sort |
first reported case of late recurrence of pulmonary mucormycosis in a renal transplant recipient with poorly controlled diabetes mellitus |
publisher |
Wiley |
publishDate |
2021 |
url |
https://doaj.org/article/22b1036d9b5540348bb5a5ece3e32856 |
work_keys_str_mv |
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