Association between abdominal aortic plaque and coronary artery disease

Wei Li,1,2,* Songyuan Luo,2,* Jianfang Luo,2 Yuan Liu,2 Wenhui Huang,2 Jiyan Chen2 1Department of Cardiology, Southern Medical University, Guangzhou, People’s Republic of China; 2Department of Cardiology, Guangdong Provincial Cardiovascular Institute, Guangdong General Hospital, Guangdong...

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Autores principales:	Li W, Luo SY, Luo JF, Liu Y, Huang WH, Chen JY
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	abdominal aortic plaque coronary artery disease ultrasound imaging atherosclerosis Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/22b50d65e5e844b4a1f179a323ca38e2
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spelling	oai:doaj.org-article:22b50d65e5e844b4a1f179a323ca38e22021-12-02T02:40:29ZAssociation between abdominal aortic plaque and coronary artery disease1178-1998https://doaj.org/article/22b50d65e5e844b4a1f179a323ca38e22016-05-01T00:00:00Zhttps://www.dovepress.com/association-between-abdominal-aortic-plaque-and-coronary-artery-diseas-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Wei Li,1,2,* Songyuan Luo,2,* Jianfang Luo,2 Yuan Liu,2 Wenhui Huang,2 Jiyan Chen2 1Department of Cardiology, Southern Medical University, Guangzhou, People’s Republic of China; 2Department of Cardiology, Guangdong Provincial Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, People’s Republic of China *These authors contributed equally to this work Objective: Currently, the association between abdominal aortic plaques and coronary artery disease (CAD) has not yet been clarified clearly. The purpose of this study was to determine the prevalence of abdominal aortic plaques by ultrasound imaging and to explore its association with CAD in patients undergoing coronary angiography.Methods: Between October 2014 and June 2015, a prospective study was conducted in the Department of Cardiology at Guangdong General Hospital, Guangzhou, People’s Republic of China. Ultrasound scanning of the abdominal aortas was performed in 1,667 consecutive patients undergoing coronary angiography. Clinical characteristics and coronary profile were collected from the patients.Results: Of the 1,667 study patients (male, 68.9%; mean age, 63±11 years) undergoing coronary angiography, 1,268 had CAD. Compared with 399 patients without CAD, 1,268 patients with CAD had higher prevalence of abdominal aortic plaques (37.3% vs 17%, P<0.001). In multivariate analysis, abdominal aortic plaques served as independent factors associated with the presence of CAD (odds ratio =2.08; 95% confidence interval =1.50–2.90; P<0.001). Of the 1,268 patients with CAD, the prevalence of abdominal aortic plaques was 27.0% (98/363) in patients with one-vessel disease, 35.0% (107/306) in patients with two-vessel disease, and 44.7% (268/599) in patients with three-vessel disease. Stepwise increases in the prevalence of abdominal aortic plaque was found depending on the number of stenotic coronary vessels (P<0.001; P-value for trend <0.001). In an ordinal logistic regression model, abdominal aortic plaques served as independent factors associated with the severity of CAD according to the number of stenotic coronary vessels (P<0.001).Conclusion: The prevalence of abdominal aortic plaques was higher in patients with CAD than in those without CAD. Abdominal aortic plaque was an independent factor associated with the presence and severity of CAD. Keywords: abdominal aortic plaque, coronary artery disease, ultrasound imaging, atherosclerosisLi WLuo SYLuo JFLiu YHuang WHChen JYDove Medical Pressarticleabdominal aortic plaquecoronary artery diseaseultrasound imagingatherosclerosisGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 11, Pp 683-688 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	abdominal aortic plaque coronary artery disease ultrasound imaging atherosclerosis Geriatrics RC952-954.6
spellingShingle	abdominal aortic plaque coronary artery disease ultrasound imaging atherosclerosis Geriatrics RC952-954.6 Li W Luo SY Luo JF Liu Y Huang WH Chen JY Association between abdominal aortic plaque and coronary artery disease
description	Wei Li,1,2,* Songyuan Luo,2,* Jianfang Luo,2 Yuan Liu,2 Wenhui Huang,2 Jiyan Chen2 1Department of Cardiology, Southern Medical University, Guangzhou, People’s Republic of China; 2Department of Cardiology, Guangdong Provincial Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, People’s Republic of China *These authors contributed equally to this work Objective: Currently, the association between abdominal aortic plaques and coronary artery disease (CAD) has not yet been clarified clearly. The purpose of this study was to determine the prevalence of abdominal aortic plaques by ultrasound imaging and to explore its association with CAD in patients undergoing coronary angiography.Methods: Between October 2014 and June 2015, a prospective study was conducted in the Department of Cardiology at Guangdong General Hospital, Guangzhou, People’s Republic of China. Ultrasound scanning of the abdominal aortas was performed in 1,667 consecutive patients undergoing coronary angiography. Clinical characteristics and coronary profile were collected from the patients.Results: Of the 1,667 study patients (male, 68.9%; mean age, 63±11 years) undergoing coronary angiography, 1,268 had CAD. Compared with 399 patients without CAD, 1,268 patients with CAD had higher prevalence of abdominal aortic plaques (37.3% vs 17%, P<0.001). In multivariate analysis, abdominal aortic plaques served as independent factors associated with the presence of CAD (odds ratio =2.08; 95% confidence interval =1.50–2.90; P<0.001). Of the 1,268 patients with CAD, the prevalence of abdominal aortic plaques was 27.0% (98/363) in patients with one-vessel disease, 35.0% (107/306) in patients with two-vessel disease, and 44.7% (268/599) in patients with three-vessel disease. Stepwise increases in the prevalence of abdominal aortic plaque was found depending on the number of stenotic coronary vessels (P<0.001; P-value for trend <0.001). In an ordinal logistic regression model, abdominal aortic plaques served as independent factors associated with the severity of CAD according to the number of stenotic coronary vessels (P<0.001).Conclusion: The prevalence of abdominal aortic plaques was higher in patients with CAD than in those without CAD. Abdominal aortic plaque was an independent factor associated with the presence and severity of CAD. Keywords: abdominal aortic plaque, coronary artery disease, ultrasound imaging, atherosclerosis
format	article
author	Li W Luo SY Luo JF Liu Y Huang WH Chen JY
author_facet	Li W Luo SY Luo JF Liu Y Huang WH Chen JY
author_sort	Li W
title	Association between abdominal aortic plaque and coronary artery disease
title_short	Association between abdominal aortic plaque and coronary artery disease
title_full	Association between abdominal aortic plaque and coronary artery disease
title_fullStr	Association between abdominal aortic plaque and coronary artery disease
title_full_unstemmed	Association between abdominal aortic plaque and coronary artery disease
title_sort	association between abdominal aortic plaque and coronary artery disease
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/22b50d65e5e844b4a1f179a323ca38e2
work_keys_str_mv	AT liw associationbetweenabdominalaorticplaqueandcoronaryarterydisease AT luosy associationbetweenabdominalaorticplaqueandcoronaryarterydisease AT luojf associationbetweenabdominalaorticplaqueandcoronaryarterydisease AT liuy associationbetweenabdominalaorticplaqueandcoronaryarterydisease AT huangwh associationbetweenabdominalaorticplaqueandcoronaryarterydisease AT chenjy associationbetweenabdominalaorticplaqueandcoronaryarterydisease
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Association between abdominal aortic plaque and coronary artery disease

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