Widespread epigenetic abnormalities suggest a broad DNA methylation erasure defect in abnormal human sperm.

<h4>Background</h4>Male-factor infertility is a common condition, and etiology is unknown for a high proportion of cases. Abnormal epigenetic programming of the germline is proposed as a possible mechanism compromising spermatogenesis of some men currently diagnosed with idiopathic infer...

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Auteurs principaux: Sahar Houshdaran, Victoria K Cortessis, Kimberly Siegmund, Allen Yang, Peter W Laird, Rebecca Z Sokol
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2007
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Accès en ligne:https://doaj.org/article/22c4699e7dba4875bc2049af3e3c75a2
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