Glia-neuron interactions underlie state transitions to generalized seizures

During epileptic seizures, neural activity across the brain switches into a hyperactive and hypersynchronized state. Here, the authors report on the role of glia-glia and glia-neuron interactions in mediating the changes that result in the ictal state in a zebrafish model of epilepsy.

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Detalles Bibliográficos
Autores principales: Carmen Diaz Verdugo, Sverre Myren-Svelstad, Ecem Aydin, Evelien Van Hoeymissen, Celine Deneubourg, Silke Vanderhaeghe, Julie Vancraeynest, Robbrecht Pelgrims, Mehmet Ilyas Cosacak, Akira Muto, Caghan Kizil, Koichi Kawakami, Nathalie Jurisch-Yaksi, Emre Yaksi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/22ccc4d2ad6d4f469da969fbd858fd86
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Sumario:During epileptic seizures, neural activity across the brain switches into a hyperactive and hypersynchronized state. Here, the authors report on the role of glia-glia and glia-neuron interactions in mediating the changes that result in the ictal state in a zebrafish model of epilepsy.