Glia-neuron interactions underlie state transitions to generalized seizures

During epileptic seizures, neural activity across the brain switches into a hyperactive and hypersynchronized state. Here, the authors report on the role of glia-glia and glia-neuron interactions in mediating the changes that result in the ictal state in a zebrafish model of epilepsy.

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Autores principales:	Carmen Diaz Verdugo, Sverre Myren-Svelstad, Ecem Aydin, Evelien Van Hoeymissen, Celine Deneubourg, Silke Vanderhaeghe, Julie Vancraeynest, Robbrecht Pelgrims, Mehmet Ilyas Cosacak, Akira Muto, Caghan Kizil, Koichi Kawakami, Nathalie Jurisch-Yaksi, Emre Yaksi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/22ccc4d2ad6d4f469da969fbd858fd86
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:22ccc4d2ad6d4f469da969fbd858fd862021-12-02T14:38:38ZGlia-neuron interactions underlie state transitions to generalized seizures10.1038/s41467-019-11739-z2041-1723https://doaj.org/article/22ccc4d2ad6d4f469da969fbd858fd862019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11739-zhttps://doaj.org/toc/2041-1723During epileptic seizures, neural activity across the brain switches into a hyperactive and hypersynchronized state. Here, the authors report on the role of glia-glia and glia-neuron interactions in mediating the changes that result in the ictal state in a zebrafish model of epilepsy.Carmen Diaz VerdugoSverre Myren-SvelstadEcem AydinEvelien Van HoeymissenCeline DeneubourgSilke VanderhaegheJulie VancraeynestRobbrecht PelgrimsMehmet Ilyas CosacakAkira MutoCaghan KizilKoichi KawakamiNathalie Jurisch-YaksiEmre YaksiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Carmen Diaz Verdugo Sverre Myren-Svelstad Ecem Aydin Evelien Van Hoeymissen Celine Deneubourg Silke Vanderhaeghe Julie Vancraeynest Robbrecht Pelgrims Mehmet Ilyas Cosacak Akira Muto Caghan Kizil Koichi Kawakami Nathalie Jurisch-Yaksi Emre Yaksi Glia-neuron interactions underlie state transitions to generalized seizures
description	During epileptic seizures, neural activity across the brain switches into a hyperactive and hypersynchronized state. Here, the authors report on the role of glia-glia and glia-neuron interactions in mediating the changes that result in the ictal state in a zebrafish model of epilepsy.
format	article
author	Carmen Diaz Verdugo Sverre Myren-Svelstad Ecem Aydin Evelien Van Hoeymissen Celine Deneubourg Silke Vanderhaeghe Julie Vancraeynest Robbrecht Pelgrims Mehmet Ilyas Cosacak Akira Muto Caghan Kizil Koichi Kawakami Nathalie Jurisch-Yaksi Emre Yaksi
author_facet	Carmen Diaz Verdugo Sverre Myren-Svelstad Ecem Aydin Evelien Van Hoeymissen Celine Deneubourg Silke Vanderhaeghe Julie Vancraeynest Robbrecht Pelgrims Mehmet Ilyas Cosacak Akira Muto Caghan Kizil Koichi Kawakami Nathalie Jurisch-Yaksi Emre Yaksi
author_sort	Carmen Diaz Verdugo
title	Glia-neuron interactions underlie state transitions to generalized seizures
title_short	Glia-neuron interactions underlie state transitions to generalized seizures
title_full	Glia-neuron interactions underlie state transitions to generalized seizures
title_fullStr	Glia-neuron interactions underlie state transitions to generalized seizures
title_full_unstemmed	Glia-neuron interactions underlie state transitions to generalized seizures
title_sort	glia-neuron interactions underlie state transitions to generalized seizures
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/22ccc4d2ad6d4f469da969fbd858fd86
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Glia-neuron interactions underlie state transitions to generalized seizures

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