Obesity-Related Indices Are Associated with Longitudinal Changes in Lung Function: A Large Taiwanese Population Follow-Up Study

The global pandemic of obesity and the increasing incidence of chronic respiratory diseases are growing health concerns. The association between obesity and pulmonary function is uncertain. Therefore, this study aimed to explore associations between changes in lung function and obesity-related indic...

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Autores principales:	Yu-En Hsu, Szu-Chia Chen, Jiun-Hung Geng, Da-Wei Wu, Pei-Yu Wu, Jiun-Chi Huang
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	obesity-related index lung function follow-up Taiwan Biobank Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/22cf51777e5a4c55b0af9b337787f80f
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spelling	oai:doaj.org-article:22cf51777e5a4c55b0af9b337787f80f2021-11-25T18:36:24ZObesity-Related Indices Are Associated with Longitudinal Changes in Lung Function: A Large Taiwanese Population Follow-Up Study10.3390/nu131140552072-6643https://doaj.org/article/22cf51777e5a4c55b0af9b337787f80f2021-11-01T00:00:00Zhttps://www.mdpi.com/2072-6643/13/11/4055https://doaj.org/toc/2072-6643The global pandemic of obesity and the increasing incidence of chronic respiratory diseases are growing health concerns. The association between obesity and pulmonary function is uncertain. Therefore, this study aimed to explore associations between changes in lung function and obesity-related indices in a large longitudinal study. A total of 9059 participants with no personal histories of asthma, smoking, bronchitis, or emphysema were enrolled from the Taiwan Biobank and followed for 4 years. Lung function was assessed using spirometry measurements including forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC). Changes in FEV1/FVC (∆FEV1/FVC) between baseline and follow-up were calculated. The following obesity-related indices were studied: lipid accumulation product (LAP), body roundness index (BRI), conicity index (CI), body adiposity index (BAI), abdominal volume index (AVI), body mass index (BMI), waist–hip ratio (WHR), and waist-to-height ratio (WHtR). In multivariable analysis, the subjects with high BMI (<i>p</i> < 0.001), WHR (<i>p</i> < 0.001), WHtR (<i>p</i> < 0.001), LAP (<i>p</i> = 0.002), BRI (<i>p</i> < 0.001), CI (<i>p</i> = 0.005), BAI (<i>p</i> < 0.001), and AVI (<i>p</i> < 0.001) were significantly associated with a high baseline FEV1/FVC. After 4 years of follow-up, the subjects with high BMI (<i>p</i> < 0.001), WHR (<i>p</i> < 0.001), WHtR (<i>p</i> < 0.001), LAP (<i>p</i> = 0.001), BRI (<i>p</i> < 0.001), CI (<i>p</i> = 0.002), BAI (<i>p</i> < 0.001), and AVI (<i>p</i> < 0.001) were significantly associated with a low △FEV1/FVC. High obesity-related index values were associated with better baseline lung function and a rapid decrease in lung function at follow-up.Yu-En HsuSzu-Chia ChenJiun-Hung GengDa-Wei WuPei-Yu WuJiun-Chi HuangMDPI AGarticleobesity-related indexlung functionfollow-upTaiwan BiobankNutrition. Foods and food supplyTX341-641ENNutrients, Vol 13, Iss 4055, p 4055 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	obesity-related index lung function follow-up Taiwan Biobank Nutrition. Foods and food supply TX341-641
spellingShingle	obesity-related index lung function follow-up Taiwan Biobank Nutrition. Foods and food supply TX341-641 Yu-En Hsu Szu-Chia Chen Jiun-Hung Geng Da-Wei Wu Pei-Yu Wu Jiun-Chi Huang Obesity-Related Indices Are Associated with Longitudinal Changes in Lung Function: A Large Taiwanese Population Follow-Up Study
description	The global pandemic of obesity and the increasing incidence of chronic respiratory diseases are growing health concerns. The association between obesity and pulmonary function is uncertain. Therefore, this study aimed to explore associations between changes in lung function and obesity-related indices in a large longitudinal study. A total of 9059 participants with no personal histories of asthma, smoking, bronchitis, or emphysema were enrolled from the Taiwan Biobank and followed for 4 years. Lung function was assessed using spirometry measurements including forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC). Changes in FEV1/FVC (∆FEV1/FVC) between baseline and follow-up were calculated. The following obesity-related indices were studied: lipid accumulation product (LAP), body roundness index (BRI), conicity index (CI), body adiposity index (BAI), abdominal volume index (AVI), body mass index (BMI), waist–hip ratio (WHR), and waist-to-height ratio (WHtR). In multivariable analysis, the subjects with high BMI (<i>p</i> < 0.001), WHR (<i>p</i> < 0.001), WHtR (<i>p</i> < 0.001), LAP (<i>p</i> = 0.002), BRI (<i>p</i> < 0.001), CI (<i>p</i> = 0.005), BAI (<i>p</i> < 0.001), and AVI (<i>p</i> < 0.001) were significantly associated with a high baseline FEV1/FVC. After 4 years of follow-up, the subjects with high BMI (<i>p</i> < 0.001), WHR (<i>p</i> < 0.001), WHtR (<i>p</i> < 0.001), LAP (<i>p</i> = 0.001), BRI (<i>p</i> < 0.001), CI (<i>p</i> = 0.002), BAI (<i>p</i> < 0.001), and AVI (<i>p</i> < 0.001) were significantly associated with a low △FEV1/FVC. High obesity-related index values were associated with better baseline lung function and a rapid decrease in lung function at follow-up.
format	article
author	Yu-En Hsu Szu-Chia Chen Jiun-Hung Geng Da-Wei Wu Pei-Yu Wu Jiun-Chi Huang
author_facet	Yu-En Hsu Szu-Chia Chen Jiun-Hung Geng Da-Wei Wu Pei-Yu Wu Jiun-Chi Huang
author_sort	Yu-En Hsu
title	Obesity-Related Indices Are Associated with Longitudinal Changes in Lung Function: A Large Taiwanese Population Follow-Up Study
title_short	Obesity-Related Indices Are Associated with Longitudinal Changes in Lung Function: A Large Taiwanese Population Follow-Up Study
title_full	Obesity-Related Indices Are Associated with Longitudinal Changes in Lung Function: A Large Taiwanese Population Follow-Up Study
title_fullStr	Obesity-Related Indices Are Associated with Longitudinal Changes in Lung Function: A Large Taiwanese Population Follow-Up Study
title_full_unstemmed	Obesity-Related Indices Are Associated with Longitudinal Changes in Lung Function: A Large Taiwanese Population Follow-Up Study
title_sort	obesity-related indices are associated with longitudinal changes in lung function: a large taiwanese population follow-up study
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/22cf51777e5a4c55b0af9b337787f80f
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Obesity-Related Indices Are Associated with Longitudinal Changes in Lung Function: A Large Taiwanese Population Follow-Up Study

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