Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing

On wounding, scar formation in mammals arises causing no hair follicle regeneration, but it is unclear if scarring precludes regeneration. Here, the authors show that if Sonic hedgehog signaling is activated in the wound, an inductive dermal niche forms, enabling regeneration and hair follicle forma...

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Autores principales:	Chae Ho Lim, Qi Sun, Karan Ratti, Soung-Hoon Lee, Ying Zheng, Makoto Takeo, Wendy Lee, Piul Rabbani, Maksim V. Plikus, Jason E. Cain, David H. Wang, D. Neil Watkins, Sarah Millar, M. Mark Taketo, Peggy Myung, George Cotsarelis, Mayumi Ito
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/22d3911c85504d6b96c4c30019908e9e
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spelling	oai:doaj.org-article:22d3911c85504d6b96c4c30019908e9e2021-12-02T14:39:04ZHedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing10.1038/s41467-018-07142-92041-1723https://doaj.org/article/22d3911c85504d6b96c4c30019908e9e2018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07142-9https://doaj.org/toc/2041-1723On wounding, scar formation in mammals arises causing no hair follicle regeneration, but it is unclear if scarring precludes regeneration. Here, the authors show that if Sonic hedgehog signaling is activated in the wound, an inductive dermal niche forms, enabling regeneration and hair follicle formation.Chae Ho LimQi SunKaran RattiSoung-Hoon LeeYing ZhengMakoto TakeoWendy LeePiul RabbaniMaksim V. PlikusJason E. CainDavid H. WangD. Neil WatkinsSarah MillarM. Mark TaketoPeggy MyungGeorge CotsarelisMayumi ItoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chae Ho Lim Qi Sun Karan Ratti Soung-Hoon Lee Ying Zheng Makoto Takeo Wendy Lee Piul Rabbani Maksim V. Plikus Jason E. Cain David H. Wang D. Neil Watkins Sarah Millar M. Mark Taketo Peggy Myung George Cotsarelis Mayumi Ito Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing
description	On wounding, scar formation in mammals arises causing no hair follicle regeneration, but it is unclear if scarring precludes regeneration. Here, the authors show that if Sonic hedgehog signaling is activated in the wound, an inductive dermal niche forms, enabling regeneration and hair follicle formation.
format	article
author	Chae Ho Lim Qi Sun Karan Ratti Soung-Hoon Lee Ying Zheng Makoto Takeo Wendy Lee Piul Rabbani Maksim V. Plikus Jason E. Cain David H. Wang D. Neil Watkins Sarah Millar M. Mark Taketo Peggy Myung George Cotsarelis Mayumi Ito
author_facet	Chae Ho Lim Qi Sun Karan Ratti Soung-Hoon Lee Ying Zheng Makoto Takeo Wendy Lee Piul Rabbani Maksim V. Plikus Jason E. Cain David H. Wang D. Neil Watkins Sarah Millar M. Mark Taketo Peggy Myung George Cotsarelis Mayumi Ito
author_sort	Chae Ho Lim
title	Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing
title_short	Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing
title_full	Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing
title_fullStr	Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing
title_full_unstemmed	Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing
title_sort	hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/22d3911c85504d6b96c4c30019908e9e
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Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing

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