DNMT3L is a regulator of X chromosome compaction and post-meiotic gene transcription.

DNMT3L is a regulator of X chromosome compaction and post-meiotic gene transcription.

Previous studies on the epigenetic regulator DNA methyltransferase 3-Like (DNMT3L), have demonstrated it is an essential regulator of paternal imprinting and early male meiosis. Dnmt3L is also a paternal effect gene, i.e., wild type offspring of heterozygous mutant sires display abnormal phenotypes...

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Autores principales: Natasha M Zamudio, Hamish S Scott, Katja Wolski, Chi-Yi Lo, Charity Law, Dillon Leong, Sarah A Kinkel, Suyinn Chong, Damien Jolley, Gordon K Smyth, David de Kretser, Emma Whitelaw, Moira K O'Bryan
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/22d443934eb24797a7ddd33f9f6272ae
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