RAD52: Paradigm of Synthetic Lethality and New Developments
DNA double-strand breaks and inter-strand cross-links are the most harmful types of DNA damage that cause genomic instability that lead to cancer development. The highest fidelity pathway for repairing damaged double-stranded DNA is termed Homologous recombination (HR). Rad52 is one of the key HR pr...
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Autores principales: | Matthew J. Rossi, Sarah F. DiDomenico, Mikir Patel, Alexander V. Mazin |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/22dfb44279204a3e8ebf84451e384a14 |
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