PRDX2 in Myocyte Hypertrophy and Survival is Mediated by TLR4 in Acute Infarcted Myocardium

Abstract Peroxiredoxin 2 (PRDX2) is an antioxidant and molecular chaperone that can be secreted from tumor cells. But the role of PRDX2 in acute myocardial infarction (AMI) is not clear. In the current study, we demonstrate the role of PRDX2 from clinical trials, H9c2 cells and in a mouse model. ELI...

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Bibliographic Details
Main Authors: Xian Jin, Chengjun Chen, Dandan Li, Qian Su, Yanwen Hang, Peng Zhang, Wei Hu
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/22e81565c2e0410a81ee9c2d38113ec1
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