PRDX2 in Myocyte Hypertrophy and Survival is Mediated by TLR4 in Acute Infarcted Myocardium
Abstract Peroxiredoxin 2 (PRDX2) is an antioxidant and molecular chaperone that can be secreted from tumor cells. But the role of PRDX2 in acute myocardial infarction (AMI) is not clear. In the current study, we demonstrate the role of PRDX2 from clinical trials, H9c2 cells and in a mouse model. ELI...
Saved in:
Main Authors: | Xian Jin, Chengjun Chen, Dandan Li, Qian Su, Yanwen Hang, Peng Zhang, Wei Hu |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
|
Subjects: | |
Online Access: | https://doaj.org/article/22e81565c2e0410a81ee9c2d38113ec1 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Increased cardiac myocyte PDE5 levels in human and murine pressure overload hypertrophy contribute to adverse LV remodeling.
by: Sara Vandenwijngaert, et al.
Published: (2013) -
Smad3 inactivation and MiR-29b upregulation mediate the effect of carvedilol on attenuating the acute myocardium infarction-induced myocardial fibrosis in rat.
by: Jie-Ning Zhu, et al.
Published: (2013) -
Acute simvastatin inhibits K ATP channels of porcine coronary artery myocytes.
by: Sai Wang Seto, et al.
Published: (2013) -
Lgals9 deficiency ameliorates obesity by modulating redox state of PRDX2
by: Tomokazu Nunoue, et al.
Published: (2021) -
Reactive oxygen species as a trigger of the infarct-limiting effects of early hypoxic preconditioning rat myocardium
by: A. S. Sementsov, et al.
Published: (2016)