Height and sex is strongly associated with radial augmentation index in Korean patients with never-treated hypertension

Kye Taek Ahn, Kwang-In Park, Mi Joo Kim, Jin Kyung Oh, Ji Hye Han, Hee Jin Kwon, Seon-Ah Jin, Jun-Hyung Kim, Jae-Hyeong Park, Jae-Hwan Lee, Si Wan Choi, In-Whan Seong, Jin-Ok Jeong Department of Internal Medicine, Division of Cardiology, Chungnam National University Hospital, Chungnam National Univ...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ahn KT, Park KI, Kim MJ, Oh JK, Han JH, Kwon HJ, Jin SA, Kim JH, Park JH, Lee JH, Choi SW, Seong IW, Jeong JO
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	Hypertension Augmentation index Height Gender Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/22eba7925b3e459c81682924df277211
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:22eba7925b3e459c81682924df277211
record_format	dspace
spelling	oai:doaj.org-article:22eba7925b3e459c81682924df2772112021-12-02T04:50:51ZHeight and sex is strongly associated with radial augmentation index in Korean patients with never-treated hypertension1178-1998https://doaj.org/article/22eba7925b3e459c81682924df2772112016-04-01T00:00:00Zhttps://www.dovepress.com/height-and-sex-is-strongly-associated-with-radial-augmentation-index-i-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Kye Taek Ahn, Kwang-In Park, Mi Joo Kim, Jin Kyung Oh, Ji Hye Han, Hee Jin Kwon, Seon-Ah Jin, Jun-Hyung Kim, Jae-Hyeong Park, Jae-Hwan Lee, Si Wan Choi, In-Whan Seong, Jin-Ok Jeong Department of Internal Medicine, Division of Cardiology, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Republic of Korea Objectives: Central hemodynamics may better represent the load imposed on the coronary and cerebral arteries and thereby bear a stronger relationship to cardiovascular outcomes. Methods: Patients who had confirmed hypertension as assessed by daytime 24-hour ambulatory blood pressure monitoring (≥135/85 mmHg) were enrolled. Central blood pressure and radial augmentation index (AIx) corrected for a heart rate of 75 bpm (radial AIx 75) were measured for all patients. We evaluated the association of age, height, and sex with central hemodynamics in patients with never-treated hypertension. Results: A total of 203 patients were enrolled, of whom men numbered 101 (49.7%). The median height of all patients was 162 cm, and mean age was 53.2 years. In the Pearson correlation analysis, regardless of sex difference (R=-0.627 for height, R=0.035 for age, P-value =0.005), a stronger relationship was observed between height and radial AIx 75 than between age and radial AIx 75. In the multiple regression analysis, the sex difference and height were strongly associated with elevated radial AIx 75 in all patients (adjusted R2=0.428, β=6.237, 95% confidence interval [CI] for women 1.480–10.995, P-value =0.011 and β=-0.632, 95% CI for height -0.929 to -0.335, P-value =0.009, respectively). Conclusion: In patients with never-treated hypertension, female sex and shorter height are the important risk factors of elevated radial AIx 75. Keywords: hypertension, augmentation index, height, sexAhn KTPark KIKim MJOh JKHan JHKwon HJJin SAKim JHPark JHLee JHChoi SWSeong IWJeong JODove Medical PressarticleHypertensionAugmentation indexHeightGenderGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 11, Pp 415-422 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Hypertension Augmentation index Height Gender Geriatrics RC952-954.6
spellingShingle	Hypertension Augmentation index Height Gender Geriatrics RC952-954.6 Ahn KT Park KI Kim MJ Oh JK Han JH Kwon HJ Jin SA Kim JH Park JH Lee JH Choi SW Seong IW Jeong JO Height and sex is strongly associated with radial augmentation index in Korean patients with never-treated hypertension
description	Kye Taek Ahn, Kwang-In Park, Mi Joo Kim, Jin Kyung Oh, Ji Hye Han, Hee Jin Kwon, Seon-Ah Jin, Jun-Hyung Kim, Jae-Hyeong Park, Jae-Hwan Lee, Si Wan Choi, In-Whan Seong, Jin-Ok Jeong Department of Internal Medicine, Division of Cardiology, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Republic of Korea Objectives: Central hemodynamics may better represent the load imposed on the coronary and cerebral arteries and thereby bear a stronger relationship to cardiovascular outcomes. Methods: Patients who had confirmed hypertension as assessed by daytime 24-hour ambulatory blood pressure monitoring (≥135/85 mmHg) were enrolled. Central blood pressure and radial augmentation index (AIx) corrected for a heart rate of 75 bpm (radial AIx 75) were measured for all patients. We evaluated the association of age, height, and sex with central hemodynamics in patients with never-treated hypertension. Results: A total of 203 patients were enrolled, of whom men numbered 101 (49.7%). The median height of all patients was 162 cm, and mean age was 53.2 years. In the Pearson correlation analysis, regardless of sex difference (R=-0.627 for height, R=0.035 for age, P-value =0.005), a stronger relationship was observed between height and radial AIx 75 than between age and radial AIx 75. In the multiple regression analysis, the sex difference and height were strongly associated with elevated radial AIx 75 in all patients (adjusted R2=0.428, β=6.237, 95% confidence interval [CI] for women 1.480–10.995, P-value =0.011 and β=-0.632, 95% CI for height -0.929 to -0.335, P-value =0.009, respectively). Conclusion: In patients with never-treated hypertension, female sex and shorter height are the important risk factors of elevated radial AIx 75. Keywords: hypertension, augmentation index, height, sex
format	article
author	Ahn KT Park KI Kim MJ Oh JK Han JH Kwon HJ Jin SA Kim JH Park JH Lee JH Choi SW Seong IW Jeong JO
author_facet	Ahn KT Park KI Kim MJ Oh JK Han JH Kwon HJ Jin SA Kim JH Park JH Lee JH Choi SW Seong IW Jeong JO
author_sort	Ahn KT
title	Height and sex is strongly associated with radial augmentation index in Korean patients with never-treated hypertension
title_short	Height and sex is strongly associated with radial augmentation index in Korean patients with never-treated hypertension
title_full	Height and sex is strongly associated with radial augmentation index in Korean patients with never-treated hypertension
title_fullStr	Height and sex is strongly associated with radial augmentation index in Korean patients with never-treated hypertension
title_full_unstemmed	Height and sex is strongly associated with radial augmentation index in Korean patients with never-treated hypertension
title_sort	height and sex is strongly associated with radial augmentation index in korean patients with never-treated hypertension
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/22eba7925b3e459c81682924df277211
work_keys_str_mv	AT ahnkt heightandsexisstronglyassociatedwithradialaugmentationindexinkoreanpatientswithnevertreatedhypertension AT parkki heightandsexisstronglyassociatedwithradialaugmentationindexinkoreanpatientswithnevertreatedhypertension AT kimmj heightandsexisstronglyassociatedwithradialaugmentationindexinkoreanpatientswithnevertreatedhypertension AT ohjk heightandsexisstronglyassociatedwithradialaugmentationindexinkoreanpatientswithnevertreatedhypertension AT hanjh heightandsexisstronglyassociatedwithradialaugmentationindexinkoreanpatientswithnevertreatedhypertension AT kwonhj heightandsexisstronglyassociatedwithradialaugmentationindexinkoreanpatientswithnevertreatedhypertension AT jinsa heightandsexisstronglyassociatedwithradialaugmentationindexinkoreanpatientswithnevertreatedhypertension AT kimjh heightandsexisstronglyassociatedwithradialaugmentationindexinkoreanpatientswithnevertreatedhypertension AT parkjh heightandsexisstronglyassociatedwithradialaugmentationindexinkoreanpatientswithnevertreatedhypertension AT leejh heightandsexisstronglyassociatedwithradialaugmentationindexinkoreanpatientswithnevertreatedhypertension AT choisw heightandsexisstronglyassociatedwithradialaugmentationindexinkoreanpatientswithnevertreatedhypertension AT seongiw heightandsexisstronglyassociatedwithradialaugmentationindexinkoreanpatientswithnevertreatedhypertension AT jeongjo heightandsexisstronglyassociatedwithradialaugmentationindexinkoreanpatientswithnevertreatedhypertension
_version_	1718400996584980480

Height and sex is strongly associated with radial augmentation index in Korean patients with never-treated hypertension

Ejemplares similares