Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin

Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin

YenTcA is the pore-forming and membrane binding subunit of the ABC toxin YenTc, which is produced by the insect pathogen Yersinia entomophaga. Here authors present cryo-EM structures of YenTcA purified from the native source which implicate associated endochitinases in host cell recognition.

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Detalles Bibliográficos
Autores principales: Sarah J Piper, Lou Brillault, Rosalba Rothnagel, Tristan I Croll, Joseph K Box, Irene Chassagnon, Sebastian Scherer, Kenneth N Goldie, Sandra A Jones, Femke Schepers, Lauren Hartley-Tassell, Thomas Ve, Jason N Busby, Julie E Dalziel, J Shaun Lott, Ben Hankamer, Henning Stahlberg, Mark R H Hurst, Michael J Landsberg
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
Q
Acceso en línea:https://doaj.org/article/22ed524a9e8c453c8589dc7718c89ba1
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Descripción
Sumario:YenTcA is the pore-forming and membrane binding subunit of the ABC toxin YenTc, which is produced by the insect pathogen Yersinia entomophaga. Here authors present cryo-EM structures of YenTcA purified from the native source which implicate associated endochitinases in host cell recognition.

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