Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin

YenTcA is the pore-forming and membrane binding subunit of the ABC toxin YenTc, which is produced by the insect pathogen Yersinia entomophaga. Here authors present cryo-EM structures of YenTcA purified from the native source which implicate associated endochitinases in host cell recognition.

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Autores principales: Sarah J Piper, Lou Brillault, Rosalba Rothnagel, Tristan I Croll, Joseph K Box, Irene Chassagnon, Sebastian Scherer, Kenneth N Goldie, Sandra A Jones, Femke Schepers, Lauren Hartley-Tassell, Thomas Ve, Jason N Busby, Julie E Dalziel, J Shaun Lott, Ben Hankamer, Henning Stahlberg, Mark R H Hurst, Michael J Landsberg
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Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/22ed524a9e8c453c8589dc7718c89ba1
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spelling oai:doaj.org-article:22ed524a9e8c453c8589dc7718c89ba12021-12-02T14:39:58ZCryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin10.1038/s41467-019-09890-82041-1723https://doaj.org/article/22ed524a9e8c453c8589dc7718c89ba12019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09890-8https://doaj.org/toc/2041-1723YenTcA is the pore-forming and membrane binding subunit of the ABC toxin YenTc, which is produced by the insect pathogen Yersinia entomophaga. Here authors present cryo-EM structures of YenTcA purified from the native source which implicate associated endochitinases in host cell recognition.Sarah J PiperLou BrillaultRosalba RothnagelTristan I CrollJoseph K BoxIrene ChassagnonSebastian SchererKenneth N GoldieSandra A JonesFemke SchepersLauren Hartley-TassellThomas VeJason N BusbyJulie E DalzielJ Shaun LottBen HankamerHenning StahlbergMark R H HurstMichael J LandsbergNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sarah J Piper
Lou Brillault
Rosalba Rothnagel
Tristan I Croll
Joseph K Box
Irene Chassagnon
Sebastian Scherer
Kenneth N Goldie
Sandra A Jones
Femke Schepers
Lauren Hartley-Tassell
Thomas Ve
Jason N Busby
Julie E Dalziel
J Shaun Lott
Ben Hankamer
Henning Stahlberg
Mark R H Hurst
Michael J Landsberg
Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin
description YenTcA is the pore-forming and membrane binding subunit of the ABC toxin YenTc, which is produced by the insect pathogen Yersinia entomophaga. Here authors present cryo-EM structures of YenTcA purified from the native source which implicate associated endochitinases in host cell recognition.
format article
author Sarah J Piper
Lou Brillault
Rosalba Rothnagel
Tristan I Croll
Joseph K Box
Irene Chassagnon
Sebastian Scherer
Kenneth N Goldie
Sandra A Jones
Femke Schepers
Lauren Hartley-Tassell
Thomas Ve
Jason N Busby
Julie E Dalziel
J Shaun Lott
Ben Hankamer
Henning Stahlberg
Mark R H Hurst
Michael J Landsberg
author_facet Sarah J Piper
Lou Brillault
Rosalba Rothnagel
Tristan I Croll
Joseph K Box
Irene Chassagnon
Sebastian Scherer
Kenneth N Goldie
Sandra A Jones
Femke Schepers
Lauren Hartley-Tassell
Thomas Ve
Jason N Busby
Julie E Dalziel
J Shaun Lott
Ben Hankamer
Henning Stahlberg
Mark R H Hurst
Michael J Landsberg
author_sort Sarah J Piper
title Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin
title_short Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin
title_full Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin
title_fullStr Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin
title_full_unstemmed Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin
title_sort cryo-em structures of the pore-forming a subunit from the yersinia entomophaga abc toxin
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/22ed524a9e8c453c8589dc7718c89ba1
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