Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors

Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors

Metaplastic breast carcinoma (MBC) is among the most aggressive subtypes of triple-negative breast cancer (TNBC) but the underlying proteome profiles are unknown. Here, the authors characterize the protein signatures of human MBC tissue samples and their relationship to TNBC and normal breast tissue...

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Autores principales: Sabra I. Djomehri, Maria E. Gonzalez, Felipe da Veiga Leprevost, Shilpa R. Tekula, Hui-Yin Chang, Marissa J. White, Ashley Cimino-Mathews, Boris Burman, Venkatesha Basrur, Pedram Argani, Alexey I. Nesvizhskii, Celina G. Kleer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
Q
Acceso en línea:https://doaj.org/article/22ef73a0f75440e0a22ac00ea2373d42
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Sumario:Metaplastic breast carcinoma (MBC) is among the most aggressive subtypes of triple-negative breast cancer (TNBC) but the underlying proteome profiles are unknown. Here, the authors characterize the protein signatures of human MBC tissue samples and their relationship to TNBC and normal breast tissue.

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