Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors

Metaplastic breast carcinoma (MBC) is among the most aggressive subtypes of triple-negative breast cancer (TNBC) but the underlying proteome profiles are unknown. Here, the authors characterize the protein signatures of human MBC tissue samples and their relationship to TNBC and normal breast tissue...

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Autores principales: Sabra I. Djomehri, Maria E. Gonzalez, Felipe da Veiga Leprevost, Shilpa R. Tekula, Hui-Yin Chang, Marissa J. White, Ashley Cimino-Mathews, Boris Burman, Venkatesha Basrur, Pedram Argani, Alexey I. Nesvizhskii, Celina G. Kleer
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/22ef73a0f75440e0a22ac00ea2373d42
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spelling oai:doaj.org-article:22ef73a0f75440e0a22ac00ea2373d422021-12-02T14:40:50ZQuantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors10.1038/s41467-020-15283-z2041-1723https://doaj.org/article/22ef73a0f75440e0a22ac00ea2373d422020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15283-zhttps://doaj.org/toc/2041-1723Metaplastic breast carcinoma (MBC) is among the most aggressive subtypes of triple-negative breast cancer (TNBC) but the underlying proteome profiles are unknown. Here, the authors characterize the protein signatures of human MBC tissue samples and their relationship to TNBC and normal breast tissue.Sabra I. DjomehriMaria E. GonzalezFelipe da Veiga LeprevostShilpa R. TekulaHui-Yin ChangMarissa J. WhiteAshley Cimino-MathewsBoris BurmanVenkatesha BasrurPedram ArganiAlexey I. NesvizhskiiCelina G. KleerNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sabra I. Djomehri
Maria E. Gonzalez
Felipe da Veiga Leprevost
Shilpa R. Tekula
Hui-Yin Chang
Marissa J. White
Ashley Cimino-Mathews
Boris Burman
Venkatesha Basrur
Pedram Argani
Alexey I. Nesvizhskii
Celina G. Kleer
Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors
description Metaplastic breast carcinoma (MBC) is among the most aggressive subtypes of triple-negative breast cancer (TNBC) but the underlying proteome profiles are unknown. Here, the authors characterize the protein signatures of human MBC tissue samples and their relationship to TNBC and normal breast tissue.
format article
author Sabra I. Djomehri
Maria E. Gonzalez
Felipe da Veiga Leprevost
Shilpa R. Tekula
Hui-Yin Chang
Marissa J. White
Ashley Cimino-Mathews
Boris Burman
Venkatesha Basrur
Pedram Argani
Alexey I. Nesvizhskii
Celina G. Kleer
author_facet Sabra I. Djomehri
Maria E. Gonzalez
Felipe da Veiga Leprevost
Shilpa R. Tekula
Hui-Yin Chang
Marissa J. White
Ashley Cimino-Mathews
Boris Burman
Venkatesha Basrur
Pedram Argani
Alexey I. Nesvizhskii
Celina G. Kleer
author_sort Sabra I. Djomehri
title Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors
title_short Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors
title_full Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors
title_fullStr Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors
title_full_unstemmed Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors
title_sort quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/22ef73a0f75440e0a22ac00ea2373d42
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