Multifunctional multi-shank neural probe for investigating and modulating long-range neural circuits in vivo

Microelectromechanical neural probes can cause tissue damage and often cannot record from distant brain areas. Here the authors combine electrical recording, optical stimulation and microfluidic drug delivery in one multi-shank probe with thinner shanks to reduce damage and a flexible design to targ...

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Autores principales: Hyogeun Shin, Yoojin Son, Uikyu Chae, Jeongyeon Kim, Nakwon Choi, Hyunjoo J. Lee, Jiwan Woo, Yakdol Cho, Soo Hyun Yang, C. Justin Lee, Il-Joo Cho
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/22f600351f714502a66107e52b1c6b0b
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Sumario:Microelectromechanical neural probes can cause tissue damage and often cannot record from distant brain areas. Here the authors combine electrical recording, optical stimulation and microfluidic drug delivery in one multi-shank probe with thinner shanks to reduce damage and a flexible design to target long-range neural circuits.