Perivascular localization of macrophages in the intestinal mucosa is regulated by Nr4a1 and the microbiome

Perivascular localization of macrophages in the intestinal mucosa is regulated by Nr4a1 and the microbiome

Lamina propria macrophages are at the frontline of defense against intestinal pathogens. Here the authors reveal that CCR2 and NR4A1-dependent CX3CR1+ macrophages form a dense network around the vessels in the lamina propria, and implicate this anatomical structure into prevention of systemic bacter...

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Autores principales: Masaki Honda, Bas G. J. Surewaard, Mayuki Watanabe, Catherine C. Hedrick, Woo-Yong Lee, Kirsty Brown, Kathy D. McCoy, Paul Kubes
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/22f602f2ddee458286f9c7576dcb809a
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